<p>(A) Representative immunoblots showing TRPM7 protein expression in HUVECs with or without HG (30 mM) for 72h. (B) The corresponding bar graphs showing relative expression of TRPM7 protein normalized to beta-actin. (C) Representative TRPM7-like currents recorded in HUVECs cultured in control or HG (30 mM) for 72h. (D) TRPM7-like current density. **<i>p</i><0.01 vs. HG; *<i>p</i><0.05 vs. control. n=4 for immunoblotting and 17-18 cells patched for current recording. </p
<p>HUVECs were transfected with transgelin 2 siRNA or a scrambled control, and followed by lovastati...
<p>(A) Representative immunoblot and quantification of PKG-I protein expression in HCMECs. (B) Repre...
This study investigated the change of transient receptor potential melastatin 7 (TRPM7) expression b...
<p>The cells were preincubated with TRPM7 siRNA or control siRNA for 48h, and then stimulated with H...
<p>(A) HUVEC were either cultured in complete growth medium (proliferating cells, P) or in starvatio...
<p>The cells were preincubated with TRPM7 siRNA or control siRNA for 48h, and then stimulated with H...
<p>(A) RT-PCR was performed on RNA extracted from HUVEC exposed to different concentrations of Mg fo...
<p>A, representative images immunocytochemistry for the detection of TRPV1 protein in cultured DRG m...
<p>The cells were preincubated with U0126 (10 μM) for 18h, then treated with TRPM7 siRNA for 48h, an...
<p>(A) A pretreatment for 10 min with the TRPM3 antagonist mefenamic acid (MFA; 20 μM) inhibits HSP7...
<p>HUVECs were cultured in normal glucose media (D-glucose, 5 mM) for 6 days (NG), high glucose medi...
<p>HUVEC were treated with 2-APB and Co(III)hexaammine or transfected with a shRNA against <i>TRPM7<...
<p>The administration of Y27632 and EHT1864 significantly attenuated the changes in EMT markers and ...
<p>(<b>A</b>) Real-time PCR for HGF mRNA shows a dose-dependent decrease in HGF production by HSC-T6...
<p>(A) Measurement of 5-MTP in HUVEC-CM by ELISA. HUVECs were treated with VEGF or pro-inflammatory ...
<p>HUVECs were transfected with transgelin 2 siRNA or a scrambled control, and followed by lovastati...
<p>(A) Representative immunoblot and quantification of PKG-I protein expression in HCMECs. (B) Repre...
This study investigated the change of transient receptor potential melastatin 7 (TRPM7) expression b...
<p>The cells were preincubated with TRPM7 siRNA or control siRNA for 48h, and then stimulated with H...
<p>(A) HUVEC were either cultured in complete growth medium (proliferating cells, P) or in starvatio...
<p>The cells were preincubated with TRPM7 siRNA or control siRNA for 48h, and then stimulated with H...
<p>(A) RT-PCR was performed on RNA extracted from HUVEC exposed to different concentrations of Mg fo...
<p>A, representative images immunocytochemistry for the detection of TRPV1 protein in cultured DRG m...
<p>The cells were preincubated with U0126 (10 μM) for 18h, then treated with TRPM7 siRNA for 48h, an...
<p>(A) A pretreatment for 10 min with the TRPM3 antagonist mefenamic acid (MFA; 20 μM) inhibits HSP7...
<p>HUVECs were cultured in normal glucose media (D-glucose, 5 mM) for 6 days (NG), high glucose medi...
<p>HUVEC were treated with 2-APB and Co(III)hexaammine or transfected with a shRNA against <i>TRPM7<...
<p>The administration of Y27632 and EHT1864 significantly attenuated the changes in EMT markers and ...
<p>(<b>A</b>) Real-time PCR for HGF mRNA shows a dose-dependent decrease in HGF production by HSC-T6...
<p>(A) Measurement of 5-MTP in HUVEC-CM by ELISA. HUVECs were treated with VEGF or pro-inflammatory ...
<p>HUVECs were transfected with transgelin 2 siRNA or a scrambled control, and followed by lovastati...
<p>(A) Representative immunoblot and quantification of PKG-I protein expression in HCMECs. (B) Repre...
This study investigated the change of transient receptor potential melastatin 7 (TRPM7) expression b...