<p>Each dot represents the percentage inhibition of compounds at concentrations of 50 µM (A), 25 µM (B), and 12.5 µM (C). (D) Antiviral effect of seven compounds confirmed by a second screening. Numbers 1–7 in the X axis represent the compounds FGIN-1-27, cilnidipine, niclosamide, UCL 2077, R(+)−butylindazone, palmitoyl-dl-carnitine chloride, and TTNPB, respectively. The dashed lines indicated the 50% inhibition in each panel.</p
The major disease targets for antiviral chemotherapy are influ-enza, rhinovirus colds and herpetic i...
The antiviral action of a new drug, 5-amino-2-(dimethylaminoethyl)-benzo-[de]-isoquinolin-1.3-dione ...
Estimated inhibition percentage (A), percentage reduction in the basic reproduction number R0 (B) an...
Japanese encephalitis virus (JEV) can cause severe central nervous disease with a high mortality rat...
<p>JEV was propagated in BHK-21 cells in the presence of different concentrations of compounds for 4...
<p>Scatter plot of primary screening data where the percentage of infected cells was normalized with...
<p>Red, pink, brown, orange circles stand for the first-generation inhibitors, i.e. Saquinavir, Rito...
a<p>The required concentration to reduce 50% of plaque formation (EC<sub>50</sub>) was calculated by...
<p>A). Efficacy of niclosamide and sixteen structurally related compounds against HRV1A infection of...
<p>(<b>A</b>) Heat map showing relative percent infection inhibition (left panel) and percent cell n...
Nine anti-herpes compounds, idoxuridine (IDU), bromovinyldeoxyuridine (BVDU), bromovinylarabinofuran...
<p>The minimal inhibitory concentration of RpSP-D and NpSP-D required to inhibit the hemagglutinatio...
<p>HeLa cells were infected with VEEV (MOI = 0.5 for 20 h), EBOV (MOI = 3 for 48 h), MARV (MOI = 3 f...
Using a highly reproducible and robust cell-based high-throughput screening (HTS) assay, the authors...
Selection of molecules inhibiting cell infection by SARS-CoV-2 from an in vitro screening covering 1...
The major disease targets for antiviral chemotherapy are influ-enza, rhinovirus colds and herpetic i...
The antiviral action of a new drug, 5-amino-2-(dimethylaminoethyl)-benzo-[de]-isoquinolin-1.3-dione ...
Estimated inhibition percentage (A), percentage reduction in the basic reproduction number R0 (B) an...
Japanese encephalitis virus (JEV) can cause severe central nervous disease with a high mortality rat...
<p>JEV was propagated in BHK-21 cells in the presence of different concentrations of compounds for 4...
<p>Scatter plot of primary screening data where the percentage of infected cells was normalized with...
<p>Red, pink, brown, orange circles stand for the first-generation inhibitors, i.e. Saquinavir, Rito...
a<p>The required concentration to reduce 50% of plaque formation (EC<sub>50</sub>) was calculated by...
<p>A). Efficacy of niclosamide and sixteen structurally related compounds against HRV1A infection of...
<p>(<b>A</b>) Heat map showing relative percent infection inhibition (left panel) and percent cell n...
Nine anti-herpes compounds, idoxuridine (IDU), bromovinyldeoxyuridine (BVDU), bromovinylarabinofuran...
<p>The minimal inhibitory concentration of RpSP-D and NpSP-D required to inhibit the hemagglutinatio...
<p>HeLa cells were infected with VEEV (MOI = 0.5 for 20 h), EBOV (MOI = 3 for 48 h), MARV (MOI = 3 f...
Using a highly reproducible and robust cell-based high-throughput screening (HTS) assay, the authors...
Selection of molecules inhibiting cell infection by SARS-CoV-2 from an in vitro screening covering 1...
The major disease targets for antiviral chemotherapy are influ-enza, rhinovirus colds and herpetic i...
The antiviral action of a new drug, 5-amino-2-(dimethylaminoethyl)-benzo-[de]-isoquinolin-1.3-dione ...
Estimated inhibition percentage (A), percentage reduction in the basic reproduction number R0 (B) an...