<p>A, Serum cholesterol lipoprotein profiles measured by size exclusion chromatography of wild type mice, human, high (90%) and low (45%) levels of repopulation in humanized FRG mice. Panel B showing percentage of different lipoprotein fractions, as well as ratio of LDL/HDL in wild type mice, human controls, repopulated FRG mice and FRG controls. C, Western blot analysis of human (h) and mouse (m) Apolipoprotein E in serum samples of human and mouse control samples, 1–6. Humanized FRG with different levels of repopulation are shown in lane 7–9.</p
<p>A. Gel filtration chromatography of 150 microliters of pooled plasma from wild type (WT), and Apo...
<p>An equal amount (20 µl) of plasma sample from each male mouse in each group (n = 4) was pooled. T...
Mouse models are a crucial and often used tool to provide insight into the underlying mechanisms of ...
<p>(A) Lipoprotein profile obtained by gel filtration–HPLC of mouse serum at 30 wk old. A representa...
Plasma levels of low density lipoproteins (LDL) and high density lipoproteins (HDL) exhibit opposing...
(A, C) Total cholesterol and triglyceride levels showed no significant differences between genotypes...
<p>[A] FPLC analysis of plasma lipoproteins: pooled plasma from female mice (N = 6). [B] Western ana...
<p><b>A,</b> Group size (n), body weights,serum cholesterol and serum triglyceride concentrations of...
<p>Blood samples were drawn after an overnight fast. (<b>A</b>) The concentrations of cholesterol, p...
<p>A. Chow diet-fed animals; ApoA-II, ApoC-III, and ApoE (identified on the right) in the fasting pl...
Rodents are poor model for human hyperlipidemias because total cholesterol and low density lipoprote...
Rodents are poor model for human hyperlipidemias because total cholesterol and low density lipoprote...
<p>A) Detection of major apolipoprotein and LDLr levels in the cortex of adult (6 month old) wild-ty...
<p>Data were mean ± SEM. LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein...
Objective: Rodents are poor model for human hyperlipidemias because total cholesterol and low densit...
<p>A. Gel filtration chromatography of 150 microliters of pooled plasma from wild type (WT), and Apo...
<p>An equal amount (20 µl) of plasma sample from each male mouse in each group (n = 4) was pooled. T...
Mouse models are a crucial and often used tool to provide insight into the underlying mechanisms of ...
<p>(A) Lipoprotein profile obtained by gel filtration–HPLC of mouse serum at 30 wk old. A representa...
Plasma levels of low density lipoproteins (LDL) and high density lipoproteins (HDL) exhibit opposing...
(A, C) Total cholesterol and triglyceride levels showed no significant differences between genotypes...
<p>[A] FPLC analysis of plasma lipoproteins: pooled plasma from female mice (N = 6). [B] Western ana...
<p><b>A,</b> Group size (n), body weights,serum cholesterol and serum triglyceride concentrations of...
<p>Blood samples were drawn after an overnight fast. (<b>A</b>) The concentrations of cholesterol, p...
<p>A. Chow diet-fed animals; ApoA-II, ApoC-III, and ApoE (identified on the right) in the fasting pl...
Rodents are poor model for human hyperlipidemias because total cholesterol and low density lipoprote...
Rodents are poor model for human hyperlipidemias because total cholesterol and low density lipoprote...
<p>A) Detection of major apolipoprotein and LDLr levels in the cortex of adult (6 month old) wild-ty...
<p>Data were mean ± SEM. LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein...
Objective: Rodents are poor model for human hyperlipidemias because total cholesterol and low densit...
<p>A. Gel filtration chromatography of 150 microliters of pooled plasma from wild type (WT), and Apo...
<p>An equal amount (20 µl) of plasma sample from each male mouse in each group (n = 4) was pooled. T...
Mouse models are a crucial and often used tool to provide insight into the underlying mechanisms of ...