Forelimb usage improved under ketogenic diet (3:1 KD) treatment in C5 hemi-contused rats (experiment 1).

<p>(A) The contusion injury produced marked deficits in rearing performance in both groups. Rats fed a 3:1 KD showed increased paw placements of their ipsilateral paw when placed simultaneously with the contralateral paw (both). (B) In a separate cohort of rats (experiment 2) we demonstrated that after switching from to a standard carbohydrate-based diet after 12-weeks of 3:1 KD treatment the forelimb usage remained elevated for 4 weeks compared to SD animals. Error bars indicate SEM. * p ≤ 0.05, ^# p=0.06 (t-test).