<p>Haplotype frequencies (HF), <i>P</i>-values (including omnibus <i>P</i>-values), and odds ratios (OR) with 95% confidence intervals (CI) are given for the strongest haplotype-disease association. Only the most significantly associated haplotypes are shown. The complete haplotype data can be found in the supplementary material. <i>P-</i>values for individual haplotypes are presented for all haplotypes with a frequency of at least 1% in the whole sample and with an omnibus haplotype <i>P-</i>value <0.05. Significant <i>P-</i>values (<0.05) are highlighted in <b>bold</b> and significant <i>P</i>-values robust to multiple testing (<i>P</i><2.5×10<sup>−3</sup><i>for omnibus P</i>-values, <i>P</i><4.8×10<sup>−4</sup> for detailed haplotype <i>...
We investigated the effect of multiple susceptibility alleles at a single disease locus on the stati...
<p><i>P</i>-values showing a trend towards significance are depicted in <i>Italic fonts</i>.</p
Characterizing the genetic contributors to complex disease traits will inevitably require considerat...
<p>Haplotypes indicated in Bold exhibited plausible association with CD. Rest of the haplotypes did ...
<p>Risk allele frequencies (RAF), allelic test empirical <i>P</i>-values (1 degree of freedom), and ...
<p>Odds ratios for haplotypes containing one or two of the allele groups of the protective class I h...
<p>The most common haplotype of 4 major alleles (GCAT) is used as a reference to derive odds ratios ...
<p>Significant p-values are in italic bold. Common Haplotypes are shown, if frequency more than 2.5%...
A haplotype is a specific sequence of nucleotides on a single chromosome. The population associa-tio...
<p>Haplotypes are encoded as 1 for major allele and 2 for minor allele see <a href="http://www.ploso...
<p>Given are the omnibus p-values for the <i>CEACAM6</i> haplotype combinations regarding CD suscept...
<p>Allelic components of the presented haplotypes are rs3787138, rs1044396 and rs3787140 SNPs, respe...
<p>Disease-associations for the different SNP-haplotype combinations with the Class II HLA haplotype...
A variety of statistical methods exist for detecting haplotype-disease association through use of ge...
<p>A total of 11 different haplotypes with frequencies >1% were identified. DLA-DRB1*00601/DQA1*0050...
We investigated the effect of multiple susceptibility alleles at a single disease locus on the stati...
<p><i>P</i>-values showing a trend towards significance are depicted in <i>Italic fonts</i>.</p
Characterizing the genetic contributors to complex disease traits will inevitably require considerat...
<p>Haplotypes indicated in Bold exhibited plausible association with CD. Rest of the haplotypes did ...
<p>Risk allele frequencies (RAF), allelic test empirical <i>P</i>-values (1 degree of freedom), and ...
<p>Odds ratios for haplotypes containing one or two of the allele groups of the protective class I h...
<p>The most common haplotype of 4 major alleles (GCAT) is used as a reference to derive odds ratios ...
<p>Significant p-values are in italic bold. Common Haplotypes are shown, if frequency more than 2.5%...
A haplotype is a specific sequence of nucleotides on a single chromosome. The population associa-tio...
<p>Haplotypes are encoded as 1 for major allele and 2 for minor allele see <a href="http://www.ploso...
<p>Given are the omnibus p-values for the <i>CEACAM6</i> haplotype combinations regarding CD suscept...
<p>Allelic components of the presented haplotypes are rs3787138, rs1044396 and rs3787140 SNPs, respe...
<p>Disease-associations for the different SNP-haplotype combinations with the Class II HLA haplotype...
A variety of statistical methods exist for detecting haplotype-disease association through use of ge...
<p>A total of 11 different haplotypes with frequencies >1% were identified. DLA-DRB1*00601/DQA1*0050...
We investigated the effect of multiple susceptibility alleles at a single disease locus on the stati...
<p><i>P</i>-values showing a trend towards significance are depicted in <i>Italic fonts</i>.</p
Characterizing the genetic contributors to complex disease traits will inevitably require considerat...