<p>(A) Schematic of the standard model used throughout the study showing the spatial dimensions of the soma and dendrite. The soma and proximal part of the dendrite had passive membrane properties while the distal, dendritic end (gray) had voltage-dependent h-conductances. (B) The somatic input impedance of a passive neuron (gray) demonstrated low-pass behavior. When h-conductances were added to the soma (magenta curve), this resulted in a band-pass filtered response. (C) If the h-conductances were located in the distal dendritic end as in panel (A), a resonance was observed in the dendritic input impedance (blue curve), but was not detectable somatically (red curve). Thin curves in panels (B) and (C) correspond to numerical results from th...
<p>(A) Considered neuron morphology with color coding the distance of each segment to the soma. (B) ...
<p>Highly-ranked models were subjected to a mixed voltage/current clamp virtual experimental protoco...
<p>A. To explore the effect of boundary conditions on a dendritic segment, different resonant lumped...
<p>Q-values of somatic input impedance (red curves) and dendro-somatic transfer impedance (black cur...
<p>(A–C): Dendro-somatic transfer impedances for an entirely passive neuron (A), a cell with h-chann...
<p>Color-coded Q-value (A) and resonant frequency (B) of the somatic input impedance (left panels) a...
Synaptic inputs to neurons are processed in a frequency-dependent manner, with either low-pass or re...
<p>Q-values of the dendritic input impedance (blue), somatic input impedance (red), and dendro-somat...
It is widely recognized that propagation of electrophysiological signals between the soma and dendri...
a, linear dependence of somatic voltage on the injected current in our realistic neuron model. The s...
<p>(A) Experimental setup for testing somatic inhibition. Red electrode shows dendritic site of stim...
<p>Input resistance (R<sub>N,D,</sub> gray dots) was measured at individual points of the motoneuron...
<p>(A,C) Two-compartment models (see <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/j...
<p>The neuron models and stimulation protocols were the same as those used in <a href="http://www.pl...
Many neurons have extensive dendritic trees, and therefore somatic voltage clamp of dendritic synaps...
<p>(A) Considered neuron morphology with color coding the distance of each segment to the soma. (B) ...
<p>Highly-ranked models were subjected to a mixed voltage/current clamp virtual experimental protoco...
<p>A. To explore the effect of boundary conditions on a dendritic segment, different resonant lumped...
<p>Q-values of somatic input impedance (red curves) and dendro-somatic transfer impedance (black cur...
<p>(A–C): Dendro-somatic transfer impedances for an entirely passive neuron (A), a cell with h-chann...
<p>Color-coded Q-value (A) and resonant frequency (B) of the somatic input impedance (left panels) a...
Synaptic inputs to neurons are processed in a frequency-dependent manner, with either low-pass or re...
<p>Q-values of the dendritic input impedance (blue), somatic input impedance (red), and dendro-somat...
It is widely recognized that propagation of electrophysiological signals between the soma and dendri...
a, linear dependence of somatic voltage on the injected current in our realistic neuron model. The s...
<p>(A) Experimental setup for testing somatic inhibition. Red electrode shows dendritic site of stim...
<p>Input resistance (R<sub>N,D,</sub> gray dots) was measured at individual points of the motoneuron...
<p>(A,C) Two-compartment models (see <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/j...
<p>The neuron models and stimulation protocols were the same as those used in <a href="http://www.pl...
Many neurons have extensive dendritic trees, and therefore somatic voltage clamp of dendritic synaps...
<p>(A) Considered neuron morphology with color coding the distance of each segment to the soma. (B) ...
<p>Highly-ranked models were subjected to a mixed voltage/current clamp virtual experimental protoco...
<p>A. To explore the effect of boundary conditions on a dendritic segment, different resonant lumped...