Differences between dGEMRIC T1 relaxation times at baseline and follow-up.

<p>Bar graphs showing the differences in dGEMRIC T1 relaxation times in each anatomical cartilage ROI at follow-up, 14 weeks after HA injections compared to baseline. The bar represents the mean and the whiskers represent the 95% confidence interval for the mean. +95 ms: clinically relevant threshold for improvement in cartilage sGAG content if a single patient is followed over time using dGEMRIC [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0079785#B24" target="_blank">24</a>]. -85 ms: clinically relevant threshold for impairment of cartilage sGAG content if a single patient is followed over time using dGEMRIC [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0079785#B24" target="_blank">24</a>]. wbFC: weight-bearing cartilage of the femoral condyle. pFC: posterior non weight-bearing cartilage of the femoral condyle. wbTP: weight-bearing cartilage of the tibial plateau.