Prediction performance comparison of single-isoform genes (green) and multi-isoform gene (blue) based on AUC (upper panel) and AUPRC (lower panel).

<p>We separately evaluated its prediction performance for single-isoform genes and multiple-isoform genes. Two-fold cross-validation was carried out to ensure enough examples in both groups. To ensure comparability, the negatives were randomly selected to ensure that the ratios of positive to negative genes for the multi-isoform group and the single isoform group are the same for each GO term. GO terms were grouped according to the number of genes in the test set. Shown in the box-plot are the AUC (<b>A</b>) and AUPRC (<b>B</b>) at 10, 25, 50, 75 and 90 percentile, respectively.