<p><b>A. Expression of SMCP in SMCP-overexpressed LHK2 cells.</b> Expression of SMCP in LHK2-SMCP cells was confirmed by RT-PCR. <b>B. Representative picture of tumors injected with SMCP-overexpressed LHK2 cells. C. Tumor growth of LHK2-SMCP cells and LHK2-Mock cells.</b> One×10<sup>3</sup> and 1×10<sup>4</sup> of LHK2-SMCP cells and LHK2-Mock cells were injected into NOD/SCID mice subcutaneously. Data are means + SD. Asterisks represents statistical significant difference. Student's t-test. <i>P</i><0.05.</p
Pyruvate kinase M2 (PKM2) is an alternatively spliced variant, which mediates the conversion of gluc...
Identifying cells of tumor origin is a fundamental question in tumor biology. Answers to this centra...
<p>(A) 1×10<sup>3</sup> ABCG2<sup>hi</sup> SP and ABCG2<sup>low</sup> NSP sorted RT112 cells were su...
<p>Two×10<sup>5</sup> LHK2 cells transfected with control siRNA or SMCP siRNA 1 and 2 were injected ...
<p>(A) Left: Subcutaneous tumors derived from SMMC-NTC, -shPKM2 cells. Middle: volumes (mm<sup>3</su...
<p><b>A. SMCP expression profiles in normal human organs.</b> SMCP mRNA expression in normal tissues...
<p><b>A. Isolation of SP cells from LHK2, MCF7 and SW480 cells.</b> Lung (LHK2), colon (SW480) and b...
<p><b>A</b>, In vivo tumor growth examined by animal assay. <b>B-C</b>, Fat pad tumor growth from mi...
<p>(A) Western blot demonstrating expression of SRC-2 and DKK4 levels in Huh7 cells. Cells were infe...
In this issue of Cancer Cell, Carretero and colleagues report that Src and FAK signaling pathways ar...
<p>Incidence indicates the number of tumor formation/number of injections.</p><p>Tumor volumes are m...
Bombesin-like peptides (BLPs) activate protein kinase C (PKC), which leads to proliferation in nonma...
<p>A549 cells were subject to stable PKCε depletion using two different shRNA lentiviruses (ε1 and ε...
Cancer stem-like cells (CSCs)/cancer-initiating cells (CICs) are defined as a small population of ca...
Small cell lung cancer (SCLC) is a neuroendocrine lung cancer characterized by fast growth, early di...
Pyruvate kinase M2 (PKM2) is an alternatively spliced variant, which mediates the conversion of gluc...
Identifying cells of tumor origin is a fundamental question in tumor biology. Answers to this centra...
<p>(A) 1×10<sup>3</sup> ABCG2<sup>hi</sup> SP and ABCG2<sup>low</sup> NSP sorted RT112 cells were su...
<p>Two×10<sup>5</sup> LHK2 cells transfected with control siRNA or SMCP siRNA 1 and 2 were injected ...
<p>(A) Left: Subcutaneous tumors derived from SMMC-NTC, -shPKM2 cells. Middle: volumes (mm<sup>3</su...
<p><b>A. SMCP expression profiles in normal human organs.</b> SMCP mRNA expression in normal tissues...
<p><b>A. Isolation of SP cells from LHK2, MCF7 and SW480 cells.</b> Lung (LHK2), colon (SW480) and b...
<p><b>A</b>, In vivo tumor growth examined by animal assay. <b>B-C</b>, Fat pad tumor growth from mi...
<p>(A) Western blot demonstrating expression of SRC-2 and DKK4 levels in Huh7 cells. Cells were infe...
In this issue of Cancer Cell, Carretero and colleagues report that Src and FAK signaling pathways ar...
<p>Incidence indicates the number of tumor formation/number of injections.</p><p>Tumor volumes are m...
Bombesin-like peptides (BLPs) activate protein kinase C (PKC), which leads to proliferation in nonma...
<p>A549 cells were subject to stable PKCε depletion using two different shRNA lentiviruses (ε1 and ε...
Cancer stem-like cells (CSCs)/cancer-initiating cells (CICs) are defined as a small population of ca...
Small cell lung cancer (SCLC) is a neuroendocrine lung cancer characterized by fast growth, early di...
Pyruvate kinase M2 (PKM2) is an alternatively spliced variant, which mediates the conversion of gluc...
Identifying cells of tumor origin is a fundamental question in tumor biology. Answers to this centra...
<p>(A) 1×10<sup>3</sup> ABCG2<sup>hi</sup> SP and ABCG2<sup>low</sup> NSP sorted RT112 cells were su...