Effect of obesity on gene expression of cyclooxygenase (COX)-1 and COX-2 isoforms in aortic perivascular adipose.

<p>Adipose was collected and analyzed from animals with monogenic (GPER⁰, <i>n</i> = 5) obesity or in diet-induced obesity (DIO, <i>n</i> = 6), as well as from lean, age-matched WT controls (<i>n</i> = 6). Expression levels of mRNA were calculated based on the 2^−ΔΔCT method and expressed as arbitrary units. GAPDH served as housekeeping control. *<i>p</i><0.01 <i>vs.</i> COX-1.