<p>Short and long-term analysis of PBMC B-cell depletion of (<b>A</b>) CD21+ and (<b>B</b>) CD21- B-cell subsets (as identified in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0080533#pone-0080533-g002" target="_blank">Figure 2C</a>). Individuals animal samples with mean shown for baseline, day 2, day 9 and day 14 post second dose (top) and percent remaining as normalized to PBS vehicle treated group (bottom) (group mean ± SD (n=4 rituximab treated groups, n=3 PBS vehicle treated groups).</p
Suppl. Figure 1. Ibrutinib treatment decreases B cell and memory B cell percentages in PBMC without ...
<p>Cells from each organ were pooled from at least three mice per group ...
<p>A) B cells in PBMC were detected by gating CD19<sup>+</sup> CD45<sup>+</sup> cells. B cell subset...
<p>PBMC analysis of (<b>A</b>) CD20 target coverage as determined by flow cytometric staining for fr...
<p>Lymph node analysis of (<b>A</b>) CD20 target coverage as determined by flow cytometric staining ...
<p>Dot plots show a comparison of B cell subsets in RA at baseline and 1-month post-BCDT for the can...
<p>Upper graph: C57BL/6 mice were injected i.v. at day 0 with 0.5 mg of a given anti-BAFF-R antibody...
The monoclonal antibody Rituximab is useful for treatment of patients with B-cell non-Hodgkin’s lymp...
<p>Freshly isolated PBMCs were incubated for two days with 22*-(20)-(20) (red) or rituximab (blue) p...
<p><b>(A)</b> Representative FACS histogram of bone marrow and splenic CD138<sup>+</sup> intracellul...
<p>B-lymphocyte numbers from immunophenotyping of peripheral blood during follow-up are shown, at ba...
<p>Peripheral blood samples from SPMS patients were surface stained for CD16, CD19, CD14, CD3, CD4, ...
<p>Percentage of remaining B cell subsets in the bone marrow and spleen in ratio to the mean of cont...
<p>(A) Representative dot plots of CD19<sup>+</sup> B cells within the CD45<sup>+</sup> lymphocyte p...
<p>Percentages of lymphocyte cell subsets CD4+ (A) and CD8+ (B) expressing CD25 for PPDB stimulated-...
Suppl. Figure 1. Ibrutinib treatment decreases B cell and memory B cell percentages in PBMC without ...
<p>Cells from each organ were pooled from at least three mice per group ...
<p>A) B cells in PBMC were detected by gating CD19<sup>+</sup> CD45<sup>+</sup> cells. B cell subset...
<p>PBMC analysis of (<b>A</b>) CD20 target coverage as determined by flow cytometric staining for fr...
<p>Lymph node analysis of (<b>A</b>) CD20 target coverage as determined by flow cytometric staining ...
<p>Dot plots show a comparison of B cell subsets in RA at baseline and 1-month post-BCDT for the can...
<p>Upper graph: C57BL/6 mice were injected i.v. at day 0 with 0.5 mg of a given anti-BAFF-R antibody...
The monoclonal antibody Rituximab is useful for treatment of patients with B-cell non-Hodgkin’s lymp...
<p>Freshly isolated PBMCs were incubated for two days with 22*-(20)-(20) (red) or rituximab (blue) p...
<p><b>(A)</b> Representative FACS histogram of bone marrow and splenic CD138<sup>+</sup> intracellul...
<p>B-lymphocyte numbers from immunophenotyping of peripheral blood during follow-up are shown, at ba...
<p>Peripheral blood samples from SPMS patients were surface stained for CD16, CD19, CD14, CD3, CD4, ...
<p>Percentage of remaining B cell subsets in the bone marrow and spleen in ratio to the mean of cont...
<p>(A) Representative dot plots of CD19<sup>+</sup> B cells within the CD45<sup>+</sup> lymphocyte p...
<p>Percentages of lymphocyte cell subsets CD4+ (A) and CD8+ (B) expressing CD25 for PPDB stimulated-...
Suppl. Figure 1. Ibrutinib treatment decreases B cell and memory B cell percentages in PBMC without ...
<p>Cells from each organ were pooled from at least three mice per group ...
<p>A) B cells in PBMC were detected by gating CD19<sup>+</sup> CD45<sup>+</sup> cells. B cell subset...