Effect of sST2 on the IL-33/ST2 pathway in VSMCs.

<p>Representative pictures of immunocytochemistry for IL-33, ST2, MyD88 and IRAK-1 are presented (<b>A</b>). mRNA levels of IL-33, sST2 and ST2L in VSMCs stimulated with sST2 (2 µg/ml) (<b>B</b>). Protein levels of IL-33, ST2-L, MyD88 and IRAK-1 are shown (<b>C</b>). All conditions were performed at least by triplicate. Histogram bars represent the mean ± SEM of 4 assays, in arbitrary units normalized to HPRT and β-actin respectively for cDNA and protein. *p<0.05 <i>vs</i>. control.