LPS-induced TNFα responsive module genes linked to transcriptional initiation, elongation and epigenetic regulation.
- Brendon P. Scicluna (295431)
- Cornelis van 't Veer (125063)
- Max Nieuwdorp (358989)
- Karen Felsmann (483910)
- Britta Wlotzka (483911)
- Erik S. G. Stroes (213339)
- Tom van der Poll (33907)
Publication date
November 2013
DOIAbstract
<p>Genes within LPS-induced TNFα responsive co-expression modules possessing epigenetic regulation, transcriptional initiation and elongation properties. kTotal, total connectivity, k. kWithin, intra-modular connectivity. kOut, extra-modular connectivity. <i>log2</i> FC LPS, log2 transformed foldchange for the placebo-treated pre- and post-LPS challenged samples. <i>log2</i> FC LPS+Etan, log2 transformed foldchange for the etanercept-treated pre- and post-LPS challenged samples. Gene names marked in bold type denote module genes identified as top module hub genes.</p
Add to ORKG