Effect of dietary gluten upon the composition of the intestinal microbiomes in NOD mice.

<p>Microbiomes of mice on gluten free chows were compared with those of mice on gluten containing chows. For the gluten free chow derived microbiomes, microbiomes from five mice on an egg-white based gluten-free chow and five from a casein-based gluten-free chow were grouped together to make a total of 10 gluten-free chow mice (▾). For the microbiomes derived from mice on gluten containing chows, five were derived from mice on standard (gluten containing) chow and five were derived from mice on gluten-supplemented casein-based chow, making a total of 10 gluten associated microbiomes (•). These were evaluated using a multi-dimensional scale analysis (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0078687#pone-0078687-g005" target="_blank">Fig 5A</a>). Richness was determined by observed Operational Taxonomic Units (OTU) (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0078687#pone-0078687-g005" target="_blank">Fig 5B</a>).