<p>Numbers of neuroblasts and immature neurons in each age group and genotype are listed for comparative purposes. Three comparisons are provided: 1) numbers of cells in 5–7 mo old NTG mice vs 13–15 mo old NTG mice; 2) numbers of cells in 5–7 mo old hAPP mice vs 13–15 mo old hAPP mice; and 3) the proportion of cells in 5–7 mo old hAPP mice relative to age-matched NTG mice vs the propotion of cells in 13–15 mo old hAPP mice relative to age-matched NTG mice.</p
BACKGROUND: Essentially all knowledge about adult hippocampal neurogenesis in humans still comes fro...
<p>ANOVA of Purkinje cell count by lobe showed that old MPS IIIB mice (white bars) had significantly...
The indusium griseum was investigated quantitatively in 5-mo-old and 18-mo-old mice. There was no di...
<p>A, Micrographs of doublecortin immunostaining in coronal brain sections from NTG and hAPP mice. B...
<p>All GC species in WT mice showed age-dependent decrease with age (from <1 d, 6–9 wks to 52 wks) i...
<p>(A–F) Representative coronal sections from <i>Aldh1a1</i><sup>−/−</sup>×<i>Aldh2</i><sup>−/−</sup...
To address the fundamental question of whether or not stem cell populations age, we performed quanti...
<p>POMC-EGFP transgenic mice were sacrificed at 1, 1.5, 2, 2.5, 3, 4, 6, 12, 18, 24 months of age by...
<p>(A) Western blot analysis. Compared to the 4- and 8-week-old mice, LRG protein levels were higher...
Adult murine neural stem cells (NSCs) generate neurons in drastically declining numbers with age. Ho...
<p>POMC-EGFP-expressing mice were sacrificed at 1, 1.5, 2, 2.5, 3, 4, 6, 12, 18, 24 months of age by...
Antral endocrine cells in four age groups of mice, namely prepubertal (1 month old), young (3 months...
Summary: Adult murine neural stem cells (NSCs) generate neurons in drastically declining numbers wit...
<p>(<b>A</b>) In the young mouse cohort (age<5.5 months), negative controls are shown in red bars (n...
Although the impact of aging on the function of the central nervous system is known, only a limited ...
BACKGROUND: Essentially all knowledge about adult hippocampal neurogenesis in humans still comes fro...
<p>ANOVA of Purkinje cell count by lobe showed that old MPS IIIB mice (white bars) had significantly...
The indusium griseum was investigated quantitatively in 5-mo-old and 18-mo-old mice. There was no di...
<p>A, Micrographs of doublecortin immunostaining in coronal brain sections from NTG and hAPP mice. B...
<p>All GC species in WT mice showed age-dependent decrease with age (from <1 d, 6–9 wks to 52 wks) i...
<p>(A–F) Representative coronal sections from <i>Aldh1a1</i><sup>−/−</sup>×<i>Aldh2</i><sup>−/−</sup...
To address the fundamental question of whether or not stem cell populations age, we performed quanti...
<p>POMC-EGFP transgenic mice were sacrificed at 1, 1.5, 2, 2.5, 3, 4, 6, 12, 18, 24 months of age by...
<p>(A) Western blot analysis. Compared to the 4- and 8-week-old mice, LRG protein levels were higher...
Adult murine neural stem cells (NSCs) generate neurons in drastically declining numbers with age. Ho...
<p>POMC-EGFP-expressing mice were sacrificed at 1, 1.5, 2, 2.5, 3, 4, 6, 12, 18, 24 months of age by...
Antral endocrine cells in four age groups of mice, namely prepubertal (1 month old), young (3 months...
Summary: Adult murine neural stem cells (NSCs) generate neurons in drastically declining numbers wit...
<p>(<b>A</b>) In the young mouse cohort (age<5.5 months), negative controls are shown in red bars (n...
Although the impact of aging on the function of the central nervous system is known, only a limited ...
BACKGROUND: Essentially all knowledge about adult hippocampal neurogenesis in humans still comes fro...
<p>ANOVA of Purkinje cell count by lobe showed that old MPS IIIB mice (white bars) had significantly...
The indusium griseum was investigated quantitatively in 5-mo-old and 18-mo-old mice. There was no di...