<p>CD14<sup>+</sup> cells (30×10<sup>3</sup> cells/well), positively selected from PBMC, were incubated for 20 hours in ELISpot plates in the presence of TGF-β (10 ng/ml) and Polymyxin B (10 µg/ml) with or without Enbrel (50 µg/ml). Black bars indicate apoE spot number without Enbrel and grey bars with Enbrel. Inflammatory cytokines were added at 10 ng/ml. Results shown are means ± SD of 4 donors. *** p<0.001, **p<0.01, ns: not significant.</p
<p>Bone marrow cells were cultured with M-CSF in the presence of NE (1 x 10<sup>-8</sup> M and 1 x 1...
<p>(a) TNF-α production in MH-S cells incubated with GCE, GCE+PMB, or GCE+aprotinin. (b) Relative MF...
<p>RAW264.7 cells (<b>A</b>) or MDM (<b>B</b>) were treated with rJHP0290 for various time points (m...
The apoE production by tissue macrophages is crucial for the prevention of atherosclerosis and the a...
<p>PBMC (100×10<sup>3</sup> cells/well) in medium containing 10 ng/ml TGF-β ( = medium only) were i...
<div><p>The apoE production by tissue macrophages is crucial for the prevention of atherosclerosis a...
<p>PBMC (100×10<sup>3</sup> cells/well) from 4 different donors were incubated for 20 hours in the p...
<p><b>A</b>) Example of how contaminating LPS in cytokine preparations can affect apoE production. T...
<p>(<b>A, B</b>) Healthy donor PBMCs were treated with different concentrations of EPs 7630 as indic...
<p>(<b>A</b>) Neutrophils (PMNL), isolated from whole blood of a patient (P1; black bars) or 3 contr...
<p>(a) Mice were treated with thioglycollate to elicit PEC, and then received 10 mg/kg APO866 by ip ...
<p>1 million PBMCs isolated from healthy −237GG (n = 9) homozygous or GA heterozygous (n = 9) donors...
<p>ApoE3 or apoE4 were complexed with extruded DMPC vesicles, then LPS was added for treatment of TH...
<p>PBMCs were labelled with CFSE and were analysed by flow cytometry after 5 days of culture. γδ-T c...
<p><b>A</b>: Expression of IL-4Rα1 and of IL-13Rα1 in non-polarized MØ<sup>B6</sup> and MØ<sup>ApoE<...
<p>Bone marrow cells were cultured with M-CSF in the presence of NE (1 x 10<sup>-8</sup> M and 1 x 1...
<p>(a) TNF-α production in MH-S cells incubated with GCE, GCE+PMB, or GCE+aprotinin. (b) Relative MF...
<p>RAW264.7 cells (<b>A</b>) or MDM (<b>B</b>) were treated with rJHP0290 for various time points (m...
The apoE production by tissue macrophages is crucial for the prevention of atherosclerosis and the a...
<p>PBMC (100×10<sup>3</sup> cells/well) in medium containing 10 ng/ml TGF-β ( = medium only) were i...
<div><p>The apoE production by tissue macrophages is crucial for the prevention of atherosclerosis a...
<p>PBMC (100×10<sup>3</sup> cells/well) from 4 different donors were incubated for 20 hours in the p...
<p><b>A</b>) Example of how contaminating LPS in cytokine preparations can affect apoE production. T...
<p>(<b>A, B</b>) Healthy donor PBMCs were treated with different concentrations of EPs 7630 as indic...
<p>(<b>A</b>) Neutrophils (PMNL), isolated from whole blood of a patient (P1; black bars) or 3 contr...
<p>(a) Mice were treated with thioglycollate to elicit PEC, and then received 10 mg/kg APO866 by ip ...
<p>1 million PBMCs isolated from healthy −237GG (n = 9) homozygous or GA heterozygous (n = 9) donors...
<p>ApoE3 or apoE4 were complexed with extruded DMPC vesicles, then LPS was added for treatment of TH...
<p>PBMCs were labelled with CFSE and were analysed by flow cytometry after 5 days of culture. γδ-T c...
<p><b>A</b>: Expression of IL-4Rα1 and of IL-13Rα1 in non-polarized MØ<sup>B6</sup> and MØ<sup>ApoE<...
<p>Bone marrow cells were cultured with M-CSF in the presence of NE (1 x 10<sup>-8</sup> M and 1 x 1...
<p>(a) TNF-α production in MH-S cells incubated with GCE, GCE+PMB, or GCE+aprotinin. (b) Relative MF...
<p>RAW264.7 cells (<b>A</b>) or MDM (<b>B</b>) were treated with rJHP0290 for various time points (m...