Vascular endothelial cell and tumor cell-derived VEGFR2 immunoreactivity on representative cases on a multi-tumor survey.

<p>Left panels, H? right panels, VEGFR2 IHC. (A) VEGFR2 IHC on renal cell carcinoma of the kidney showed endothelial cell immunoreactivity (×400). (B) VEGFR2 IHC on ADC of the colon showed endothelial cell immunoreactivity in the stromal mucosa. Tumor cells were negative for VEGFR2 (×400). (C) VEGFR2 IHC on SCC of the lung showed endothelial cell and a range of tumor cell-derived nuclear, cytoplasmic, and membranous immunoreactivity (×200). (D) VEGFR2 IHC showed vascular endothelial cell immunoreactivity and a range of tumor cell cytoplasmic and nuclear immunoreactivity on SCC of the cervix (×200). Immunoreactivity in endothelial cells lining vessels (white and black arrows). Slides were counterstained with hematoxylin. Scale bars: 50 µm.