Tumor-infiltrating CD4⁺CD25⁺ cells up-regulate FoxP3 and TGF-β expression upon activation.

<p>(<b>A</b>) Shown are two dots plots of purified tumor-infiltrating CD4⁺ T cells stimulated with ConA or media alone. Cells are gated on CD4 and CD25. (<b>B</b>) Bar charts showing the mean (± SEM, <i>n</i>=3 unique patient samples) percentage of FoxP3⁺ and TGF-β T cells among the total CD4⁺CD25⁺ T cells stimulated with either ConA or media alone. P value obtained by a paired Student’s T test.