Erlotinib inhibits growth of the chordoma PDX.

<p>A. Growth curves of animals treated with vehicle (red line) or erlotinib (50 mg/kg, blue line) (p = 0.002). The growth curve of vehicle treated animals was censored at 37 days as tumors in two animals in this group reached 2,000 mm³ at this time point and were euthanized. B. Representative mice bearing flank xenografts treated with vehicle (left) and erlotinib (right).