Apolipoprotein-e (APOE) ε genotype and hippocampal volumes.

Summary of unadjusted hippocampal volumes by APOE ε2 allele dose and diagnostic category.

Christopher A. Hostage (284724)
Kingshuk Roy Choudhury (284725)
Pudugramam Murali Doraiswamy (284726)
Jeffrey R. Petrella (35721)

February 2013

Unadjusted values. “ε2 dose” = copy number of APOE ε2 allele,“SD” = standard deviation, “S...

Alzheimer’s Disease Susceptibility Genes APOE and TOMM40, and Hippocampal Volumes in the Lothian Birth Cohort 1936

Lyall, Donald M
Royle, Natalie A
Harris, Sarah E
Bastin, Mark E
Maniega, Susana Muñoz
Murray, Catherine
Lutz, Michael W
Saunders, Ann M
Roses, Allen D
del Valdés Hernández, Maria C
Starr, John M
Porteous, David J
Wardlaw, Joanna M
Deary, Ian J

November 2013

The APOE ε and TOMM40 rs10524523 (‘523’) variable length poly-T repeat gene loci have been significa...

Structural brain volume differences between cognitively intact ApoE4 carriers and non-carriers across the lifespan

Ryan J Piers

January 2018

Apolipoprotein E4 (ApoE4) is a prominent genetic risk factor for Alzheimer's disease. The purpose of...

Translocase of outer membrane 40 (TOMM40) ‘523’ poly-T repeat genotype and hippocampal volumes.

Donald M. Lyall (586609)
Natalie A. Royle (483280)
Sarah E. Harris (107676)
Mark E. Bastin (446128)
Susana Muñoz Maniega (483281)
Catherine Murray (446129)
Michael W. Lutz (332695)
Ann M. Saunders (332694)
Allen D. Roses (268034)
Maria C. del Valdés Hernández (586610)
John M. Starr (107707)
David. J. Porteous (586611)
Joanna M. Wardlaw (202445)
Ian J. Deary (107724)

November 2013

Note. Age at time of testing and gender statistically controlled. ICV-corrected = intracranial vo...

Descriptive statistics for raw hippocampal, intracranial and total brain tissue volumes, grouped by genotype.

Donald M. Lyall (586609)
Natalie A. Royle (483280)
Sarah E. Harris (107676)
Mark E. Bastin (446128)
Susana Muñoz Maniega (483281)
Catherine Murray (446129)
Michael W. Lutz (332695)
Ann M. Saunders (332694)
Allen D. Roses (268034)
Maria C. del Valdés Hernández (586610)
John M. Starr (107707)
David. J. Porteous (586611)
Joanna M. Wardlaw (202445)
Ian J. Deary (107724)

November 2013

Note. All volumes are in mm3, estimated marginal means adjusted for age and gender. IC...

Dissecting the gene dose-effects of the APOE ε4 and ε2 alleles on hippocampal volumes in aging and Alzheimer's disease.

Christopher A Hostage
Kingshuk Roy Choudhury
Pudugramam Murali Doraiswamy
Jeffrey R Petrella

To investigate whether there is a specific dose-dependent effect of the Apolipoprotein E (APOE) ε4 a...

A Multi-Cohort Study of ApoE epsilon 4 and Amyloid-beta Effects on the Hippocampus in Alzheimer's Disease

Khan, W
Giampietro, V
Banaschewski, T
Barker, GJ
Bokde, ALW
Buechel, C
Conrod, P
Flor, H
Frouin, V
Garavan, H
Gowland, P
Heinz, A
Ittermann, B
Lemaitre, H
Nees, F
Paus, T
Pausova, Z
Rietschel, M
Smolka, MN
Stroehle, A
Gallinat, J
Vellas, B
Soininen, H
Kloszewska, I
Tsolaki, M
Mecocci, P
Spenger, C
Villemagne, VL
Masters, CL
Muehlboeck, J-S
Backman, L
Fratiglioni, L
Kalpouzos, G
Wahlund, L-O
Schumann, G
Lovestone, S
Williams, SCR
Westman, E
Simmons, A

January 2017

The apolipoprotein E (APOE) gene has been consistently shown to modulate the risk of Alzheimer's dis...

Effect of Apolipoprotein ε4 on Hippocampal and Brain Volume in Intractable Temporal Lobe Epilepsy

Busch, Robyn M.
Floden, Darlene
Lineweaver, Tara T.
Chapin, Jessica S.
Ungwongse, Kanjana
Wehner, Tim
Diaz-Arrastia, Ramon
Najm, Imad M.

January 2011

This study investigated the relationship between the apolipoprotein (APOE) ε4 allele and brain volum...

Low Plasma ApoE Levels Are Associated with Smaller Hippocampal Size in the Alzheimer's Disease Neuroimaging Initiative Cohort

Teng, Edmond
Chow, Nicole
Hwang, Kristy S
Thompson, Paul M
Gylys, Karen H
Cole, Gregory M
Jack, Clifford R
Shaw, Leslie M
Trojanowski, John Q
Soares, Holly D
Weiner, Michael W
Apostolova, Liana G

January 2015

Apolipoprotein E (APOE) genotype is the strongest known genetic risk factor for sporadic Alzheimer's...

Supplementary Material for: Low Plasma ApoE Levels Are Associated with Smaller Hippocampal Size in the Alzheimer's Disease Neuroimaging Initiative Cohort

Teng E. (4142170)
Chow N. (4149559)
Hwang K.S. (4149565)
Thompson P.M. (4149574)
Gylys K.H. (4149577)
Cole G.M. (4149571)
Jack Jr. C.R. (4145578)
Shaw L.M. (4149568)
Trojanowski J.Q. (4149562)
Soares H.D. (4149556)

December 2014

Apolipoprotein E (APOE) genotype is the strongest known genetic risk factor for sporadic Alzh...

Influence of APOE Genotype on Hippocampal Atrophy over Time - An N=1925 Surface-Based ADNI Study.

Bolun Li
Jie Shi
Boris A Gutman
Leslie C Baxter
Paul M Thompson
Richard J Caselli
Yalin Wang

The apolipoprotein E (APOE) e4 genotype is a powerful risk factor for late-onset Alzheimer's disease...

Apolipoprotein E Polymorphisms Associated with Reduced Subcortical Volume and Cortical Thickness in Healthy Middle-Aged Adults

Scherkenbach, Hannah

April 2016

The pathology associated with Alzheimer\u27s disease (AD) includes hippocampal atrophy and medial te...

Posterior Cingulate Glucose Metabolism, Hippocampal Glucose Metabolism, and Hippocampal Volume in Cognitively Normal, Late-Middle-Aged Persons at 3 Levels of Genetic Risk for Alzheimer Disease

Protas, Hillary D
Chen, Kewei
Langbaum, Jessica BS
Fleisher, Adam S
Alexander, Gene E
Lee, Wendy
Bandy, Daniel
de Leon, Mony J
Mosconi, Lisa
Buckley, Shannon
Truran-Sacrey, Diana
Schuff, Norbert
Weiner, Michael W
Caselli, Richard J
Reiman, Eric M

March 2013

ObjectiveTo characterize and compare measurements of the posterior cingulate glucose metabolism, the...

Volume of the human hippocampus as determined by MRI.

Christina Rose Kyrtsos (810935)
John S. Baras (810936)

October 2015

MCI, mild cognitive impairment; AD, Alzheimer’s disease. Volume loss was approximately 1% in heal...

Summary of unadjusted hippocampal volumes by APOE ε4 allele dose and diagnostic category.

Christopher A. Hostage (284724)
Kingshuk Roy Choudhury (284725)
Pudugramam Murali Doraiswamy (284726)
Jeffrey R. Petrella (35721)

February 2013

Unadjusted values. “ε4 dose” = copy number of APOE ε4 allele,“SD” = standard deviation, “S...

Summary of unadjusted hippocampal volumes by APOE ε2 allele dose and diagnostic category.

Christopher A. Hostage (284724)
Kingshuk Roy Choudhury (284725)
Pudugramam Murali Doraiswamy (284726)
Jeffrey R. Petrella (35721)

February 2013

Unadjusted values. “ε2 dose” = copy number of APOE ε2 allele,“SD” = standard deviation, “S...

Alzheimer’s Disease Susceptibility Genes APOE and TOMM40, and Hippocampal Volumes in the Lothian Birth Cohort 1936

Lyall, Donald M
Royle, Natalie A
Harris, Sarah E
Bastin, Mark E
Maniega, Susana Muñoz
Murray, Catherine
Lutz, Michael W
Saunders, Ann M
Roses, Allen D
del Valdés Hernández, Maria C
Starr, John M
Porteous, David J
Wardlaw, Joanna M
Deary, Ian J

November 2013

The APOE ε and TOMM40 rs10524523 (‘523’) variable length poly-T repeat gene loci have been significa...

Structural brain volume differences between cognitively intact ApoE4 carriers and non-carriers across the lifespan

Ryan J Piers

January 2018

Apolipoprotein E4 (ApoE4) is a prominent genetic risk factor for Alzheimer's disease. The purpose of...

Translocase of outer membrane 40 (TOMM40) ‘523’ poly-T repeat genotype and hippocampal volumes.

Donald M. Lyall (586609)
Natalie A. Royle (483280)
Sarah E. Harris (107676)
Mark E. Bastin (446128)
Susana Muñoz Maniega (483281)
Catherine Murray (446129)
Michael W. Lutz (332695)
Ann M. Saunders (332694)
Allen D. Roses (268034)
Maria C. del Valdés Hernández (586610)
John M. Starr (107707)
David. J. Porteous (586611)
Joanna M. Wardlaw (202445)
Ian J. Deary (107724)

November 2013

Note. Age at time of testing and gender statistically controlled. ICV-corrected = intracranial vo...

Descriptive statistics for raw hippocampal, intracranial and total brain tissue volumes, grouped by genotype.

Donald M. Lyall (586609)
Natalie A. Royle (483280)
Sarah E. Harris (107676)
Mark E. Bastin (446128)
Susana Muñoz Maniega (483281)
Catherine Murray (446129)
Michael W. Lutz (332695)
Ann M. Saunders (332694)
Allen D. Roses (268034)
Maria C. del Valdés Hernández (586610)
John M. Starr (107707)
David. J. Porteous (586611)
Joanna M. Wardlaw (202445)
Ian J. Deary (107724)

November 2013

Note. All volumes are in mm3, estimated marginal means adjusted for age and gender. IC...

Dissecting the gene dose-effects of the APOE ε4 and ε2 alleles on hippocampal volumes in aging and Alzheimer's disease.

Christopher A Hostage
Kingshuk Roy Choudhury
Pudugramam Murali Doraiswamy
Jeffrey R Petrella

To investigate whether there is a specific dose-dependent effect of the Apolipoprotein E (APOE) ε4 a...

A Multi-Cohort Study of ApoE epsilon 4 and Amyloid-beta Effects on the Hippocampus in Alzheimer's Disease

Khan, W
Giampietro, V
Banaschewski, T
Barker, GJ
Bokde, ALW
Buechel, C
Conrod, P
Flor, H
Frouin, V
Garavan, H
Gowland, P
Heinz, A
Ittermann, B
Lemaitre, H
Nees, F
Paus, T
Pausova, Z
Rietschel, M
Smolka, MN
Stroehle, A
Gallinat, J
Vellas, B
Soininen, H
Kloszewska, I
Tsolaki, M
Mecocci, P
Spenger, C
Villemagne, VL
Masters, CL
Muehlboeck, J-S
Backman, L
Fratiglioni, L
Kalpouzos, G
Wahlund, L-O
Schumann, G
Lovestone, S
Williams, SCR
Westman, E
Simmons, A

January 2017

The apolipoprotein E (APOE) gene has been consistently shown to modulate the risk of Alzheimer's dis...

Effect of Apolipoprotein ε4 on Hippocampal and Brain Volume in Intractable Temporal Lobe Epilepsy

Busch, Robyn M.
Floden, Darlene
Lineweaver, Tara T.
Chapin, Jessica S.
Ungwongse, Kanjana
Wehner, Tim
Diaz-Arrastia, Ramon
Najm, Imad M.

January 2011

This study investigated the relationship between the apolipoprotein (APOE) ε4 allele and brain volum...

Low Plasma ApoE Levels Are Associated with Smaller Hippocampal Size in the Alzheimer's Disease Neuroimaging Initiative Cohort

Teng, Edmond
Chow, Nicole
Hwang, Kristy S
Thompson, Paul M
Gylys, Karen H
Cole, Gregory M
Jack, Clifford R
Shaw, Leslie M
Trojanowski, John Q
Soares, Holly D
Weiner, Michael W
Apostolova, Liana G

January 2015

Apolipoprotein E (APOE) genotype is the strongest known genetic risk factor for sporadic Alzheimer's...

Supplementary Material for: Low Plasma ApoE Levels Are Associated with Smaller Hippocampal Size in the Alzheimer's Disease Neuroimaging Initiative Cohort

Teng E. (4142170)
Chow N. (4149559)
Hwang K.S. (4149565)
Thompson P.M. (4149574)
Gylys K.H. (4149577)
Cole G.M. (4149571)
Jack Jr. C.R. (4145578)
Shaw L.M. (4149568)
Trojanowski J.Q. (4149562)
Soares H.D. (4149556)

December 2014

Apolipoprotein E (APOE) genotype is the strongest known genetic risk factor for sporadic Alzh...

Influence of APOE Genotype on Hippocampal Atrophy over Time - An N=1925 Surface-Based ADNI Study.

Bolun Li
Jie Shi
Boris A Gutman
Leslie C Baxter
Paul M Thompson
Richard J Caselli
Yalin Wang

The apolipoprotein E (APOE) e4 genotype is a powerful risk factor for late-onset Alzheimer's disease...

Apolipoprotein E Polymorphisms Associated with Reduced Subcortical Volume and Cortical Thickness in Healthy Middle-Aged Adults

Scherkenbach, Hannah

April 2016

The pathology associated with Alzheimer\u27s disease (AD) includes hippocampal atrophy and medial te...

Posterior Cingulate Glucose Metabolism, Hippocampal Glucose Metabolism, and Hippocampal Volume in Cognitively Normal, Late-Middle-Aged Persons at 3 Levels of Genetic Risk for Alzheimer Disease

Protas, Hillary D
Chen, Kewei
Langbaum, Jessica BS
Fleisher, Adam S
Alexander, Gene E
Lee, Wendy
Bandy, Daniel
de Leon, Mony J
Mosconi, Lisa
Buckley, Shannon
Truran-Sacrey, Diana
Schuff, Norbert
Weiner, Michael W
Caselli, Richard J
Reiman, Eric M

March 2013

ObjectiveTo characterize and compare measurements of the posterior cingulate glucose metabolism, the...

Volume of the human hippocampus as determined by MRI.

Christina Rose Kyrtsos (810935)
John S. Baras (810936)

October 2015

MCI, mild cognitive impairment; AD, Alzheimer’s disease. Volume loss was approximately 1% in heal...

Summary of unadjusted hippocampal volumes by APOE ε4 allele dose and diagnostic category.

Christopher A. Hostage (284724)
Kingshuk Roy Choudhury (284725)
Pudugramam Murali Doraiswamy (284726)
Jeffrey R. Petrella (35721)

February 2013

Unadjusted values. “ε4 dose” = copy number of APOE ε4 allele,“SD” = standard deviation, “S...

Summary of unadjusted hippocampal volumes by APOE ε2 allele dose and diagnostic category.

Christopher A. Hostage (284724)
Kingshuk Roy Choudhury (284725)
Pudugramam Murali Doraiswamy (284726)
Jeffrey R. Petrella (35721)

February 2013

Unadjusted values. “ε2 dose” = copy number of APOE ε2 allele,“SD” = standard deviation, “S...

Alzheimer’s Disease Susceptibility Genes APOE and TOMM40, and Hippocampal Volumes in the Lothian Birth Cohort 1936

Lyall, Donald M
Royle, Natalie A
Harris, Sarah E
Bastin, Mark E
Maniega, Susana Muñoz
Murray, Catherine
Lutz, Michael W
Saunders, Ann M
Roses, Allen D
del Valdés Hernández, Maria C
Starr, John M
Porteous, David J
Wardlaw, Joanna M
Deary, Ian J

November 2013

The APOE ε and TOMM40 rs10524523 (‘523’) variable length poly-T repeat gene loci have been significa...

Structural brain volume differences between cognitively intact ApoE4 carriers and non-carriers across the lifespan

Ryan J Piers

January 2018

Apolipoprotein E4 (ApoE4) is a prominent genetic risk factor for Alzheimer's disease. The purpose of...

Apolipoprotein-e (<i>APOE</i>) ε genotype and hippocampal volumes.

Abstract

Extracted data

Apolipoprotein-e (<i>APOE</i>) ε genotype and hippocampal volumes.

Abstract

Extracted data

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