Effects of EAF2 loss on C57BL/6J and FVB/NJ mouse prostate.
- Laura E. Pascal (486278)
- Junkui Ai (486279)
- Khalid Z. Masoodi (486280)
- Yujuan Wang (436153)
- Dan Wang (34472)
- Kurtis Eisermann (95302)
- Lora H. Rigatti (486281)
- Katherine J. O’Malley (486282)
- Hei M. Ma (486283)
- Xinhui Wang (126681)
- Javid A. Dar (486284)
- Anil V. Parwani (486285)
- Brian W. Simons (486286)
- Michael M. Ittman (486287)
- Luyuan Li (486288)
- Benjamin J. Davies (486289)
- Zhou Wang (486290)
DOIAbstract
<p>A. Incidence in prostate epithelial hyperplasia (Epi) and stromal defects (Str) in C57BL/6J EAF2<sup>−/−</sup> mice at age 7 wks and 19 wks compared to 0% incidence in age-matched wild-type controls. B. CD31<sup>+</sup> microvessel density in C57BL/6J wild-type (WT) and EAF2<sup>−/−</sup> mice at age 7 wks and 19 wks. Data represent average of 9 C57BL/6J mice per group. C. Percentage of Ki-67 positive epithelial cells in the ventral (vp), dorsal-lateral (dlp), and anterior (ap) prostate of wild-type (WT), EAF2<sup>+/−</sup> and EAF2<sup>−/−</sup> FVB/NJ mice at age 20 mos. D. CD31<sup>+</sup> microvessel density in FVB/NJ WT and EAF2−/− mice at age 20 mos. Data represent average of 3 FVB/NJ mice per group. (*p<0.05, **p<0.001, ***p<0.000...
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