Tellurite/CTX damage in <i>E. coli</i>.
- Roberto C. Molina-Quiroz (325699)
- David E. Loyola (486379)
- Claudia M. Muñoz-Villagrán (325700)
- Raquel Quatrini (30066)
- Claudio C. Vásquez (23058)
- José M. Pérez-Donoso (117203)
Publication date
November 2013
DOIAbstract
<p>Peptidoglycan integrity (stability) is affected by CTX (1), favoring tellurite entry (2). Tellurite/CTX administration generates global transcriptional changes on different stress response pathways, transport, [Fe-S] clusters assembly, protein folding and different oxidative stress regulators (3). Finally, CTX and tellurite generate hydroxyl radical and superoxide respectively, damaging DNA, proteins and most probably other macromolecules.</p
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