Response of Sim1creiDTR and iDTR mice to high fat diet.

<p>(A) Food intake and (B) energy intake of Sim1creiDTR and iDTR mice. Mice were fed with chow for a week, switched to HF for a week, then back to chow(n=6 for each group). (C) Average daily body weight change of Sim1creiDTR and iDTR mice when fed with a chow diet or HF diet (n=6 for each group). (D)(E)Daily food intake (E) and energy intake (F) of Sim1creiDTR and iDTR mice fed with mixed diet of chow and HF (n=7 to 9 for each group). * p<0.05.