Collagen monomers increase M2 marker production by AM.

<p>M2 cytokine production of BAL cells stimulated with monomers of various collagen types. M2 cytokine production of BAL cells from 5 additional patients with IPF are depicted in black and 5 additional experiments with BAL cells from healthy donors are depicted in grey. <b>Panel A</b> shows CCL18 production following stimulation with rat collagen-I (Col 1R; 100µg/ml), human collagen-I (Col I, 100 µg/ml), human collagen-III (Col III, 100 µg/ml), human collagen-IV (Col IV, 100 µg/ml), human collagen-V (Col V, 100 µg/ml). <b>Panel B</b> shows IL-1ra production following the same stimulation protocol. <b>Panel C</b> shows CCL2 production. *p<0.05.