Identification of modifying genes with undetermined roles in <i>dNf1</i> suppression.

<p>(A) Validation of <i>NAAT1</i>, <i>HERC2</i> and <i>Hs3st-B</i> as <i>dNf1</i> modifiers. All three genes were identified by systematic RNAi screening of genes uncovered by suppressing deficiencies. (B) Loss-of-function alleles of Class C Vacuolar Protein Sorting complex subunits <i>carnation</i> (<i>car/Vps33A</i>) and <i>deep-orange</i> (<i>dor/Vps18</i>) increase <i>dNf1</i> pupal size. C) RNAi-mediated neuronal <i>car</i> or <i>dor</i> knockdown was not particularly effective, suggesting these genes may function elsewhere to modify <i>dNf1</i>-dependent growth.