Quantification of pulmonary pathology and bacterial burden.

<p>(A and B) The sum of gross lesions (GL) volumes in lungs (measured by CT) and thoracic LN (measured by direct visual examination) is expressed in cm³, and the total bacterial counts in thoracic LN are expressed as Log₁₀-transformed CFU. Horizontal lines indicate mean values. ***<i>P<</i>0.001, one-way ANOVA/Student-Newman-Keuls multiple comparison test. (C) Correlation between the volume of GL and bacterial counts. Results are divided according to treatment groups (BCG, circles; BCG-AdTBF, diamonds; and Control, triangles). *<i>P<</i>0.05, Pearson’s correlation (r).