Knockdown of galectin-3 changes the activity of caspase 3, 8 and 9 after epirubicin treatment.

<p>The effect of treatment with CTR, scrambled shRNA, shGal-3, overGal-3, and/or Epi for 48 h on caspase-3, caspase-8, and caspase-9 activity levels in Caco-2 cells. Data are presented as the means ± SD from three independent experiments. <b><i>^*</i></b>, <i>P</i> < 0.05 compared with CTR; ^†, <i>P</i> < 0.05 compared with shGal-3; ^‡, <i>P</i> < 0.05 compared with Epi; ^§, <i>P</i> < 0.05 compared with overGal-3.