Changes of MSCs in culture.

<p>Cultured in growth medium, MSCs in passage (P) 10 were larger and fatter compared to cells in P1 (A & B). Real-Time PCR analysis showed expressional changes of genes involved in stem cell pluripotency and osteogenic differentiation (C). The experiment was repeated three time with similar results, and representative results from one experiment were shown (*<i>P</i><0.01). ALP, asalkaline phosphatase; OPN, osteopontin.