TLR, cytokine, and transcription factor expression levels in pDLCs are distinct from pDCs and mDCs.
- Yohei Osaki (491181)
- Akihiko Yokohama (491182)
- Akio Saito (491183)
- Kenichi Tahara (491184)
- Kunio Yanagisawa (491185)
- Yoshiyuki Ogawa (491186)
- Takuma Ishizaki (372942)
- Takeki Mitsui (491187)
- Hiromi Koiso (491188)
- Makiko Takizawa (491189)
- Hideki Uchiumi (491190)
- Takayuki Saitoh (5657026)
- Hiroshi Handa (7692)
- Hirokazu Murakami (115423)
- Norifumi Tsukamoto (491191)
- Yoshihisa Nojima (184788)
Publication date
November 2013
DOIAbstract
<p>qRT-PCR analyses were performed using cDNA from pDLCs, pDCs, and mDCs. Results were standardized using PBMC cDNA (n=5). * P < 0.05 compared to pDLC. (A) TLR expression analysis revealed that mDCs expressed TLR2 and TLR4, whereas pDCs expressed TLR7 and TLR9. (B) Cytokine production was analyzed after CpG or LPS stimulation. (C) Transcripts of E2-2, Id2, Irf8, PU.1, and SpiB were analyzed in pDLCs, pDCs, and mDCs.</p
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