Heatmap of intensity of antibody binding to immunogenic <i>P. falciparum</i> proteins by sera from study groups.

<p>The gradient heatmap depicts z-scores of signal intensity values of antibody binding to 107 proteins considered immunogenic by sera from naturally exposed individuals from the Kenyan highlands. Gradient colors indicate the range of z-score values as the number of standard deviations above the mean of unexposed controls from 0 (green) to 5 (black) to 10 or more (red). Sera cohorts are stratified by site and season of sample collection, and age of sample donors (0-4, 5-14 and >15 years old). Proteins are listed by averaged intensity of response amongst all sera groups; description of the function and in some cases the gene ID for the ORF of each protein is shown. The number of serum samples tested in each sera group is provided on the bottom of the heatmap.