*<p>Average age of <i>TgK19GT<sub>121</sub>; β-actin Cre</i> mice analyzed here was 123 days (2–6 months, mainly line 43) and <i>TgK18GT<sub>121</sub>; β-actin Cre</i> mice 130 days (1–6 months, both lines). Three <i>TgK19GT<sub>121</sub>; β-actin Cre</i> mice were euthanized due to kidney hydronephrosis at 2 months of age. All <i>TgK18GT<sub>121</sub>; β-actin Cre</i> mice were euthanized due to thymic masses at 1–6 months of age.</p>†<p>The onset and extent of lesions were different between <i>TgK19GT<sub>121</sub>; β-actin Cre</i> and <i>TgK18GT<sub>121</sub>; β-actin Cre</i> mice (see text for details).</p>#<p>multifocal hyperplasia. m: male; f: female; N.D.: not determined.</p
<p>For each organ, the severity score is highest in the hu7/8 BAC+ x <i>MyD88</i> WT mice (left grou...
<p>Spongiosis, astrogliosis, and PrP deposition were ranked for severity and grouped by days post in...
<p>(A) Representative images of paraffin kidney sections stained with HE in control (CTL) and <i>Ppa...
<p>Hyperplasia was observed in some tissues (ovary and prostate: indicated by arrows). All mice were...
<p>Proliferation rates of pancreas, mammary gland, ovary, prostate (dorsolateral lobe), and bladder ...
Detailed histopathological diagnoses of inbred mouse strains are important for interpreting research...
The 129 mouse strain is commonly used for the generation of genetically engineered mice. Genetic dri...
The 129 mouse strain is commonly used for the generation of genetically engineered mice. Genetic dri...
<p>Histological findings in CXCL10 KO, and HBZ-Tg/CXCL10 KO mice at 24 weeks of age.</p
<p>(A) Photographs show dorsal aspect of <i>OX40<sup>Cre</sup> Ikbk2<sup>fx/fx</sup></i> mice with v...
<p>Histological findings in WT, HBZ-Tg, IFN-γ KO, and HBZ-Tg/IFN-γ KO mice at 24 weeks of age.</p
<p>(A) Representative images of Hematoxylin & Eosin (HE) stained livers from young (12-week-old) lit...
<p>Development of foci of cellular alteration (FCA), the proliferating cell nuclear antigen (PCNA)-l...
<p>(A) Photograph shows skin pathology in a representative <i>Rag1</i><sup>−/− </sup><i>OX40<sup>Cre...
<p>(A) Representative images of Masson trichrome stained livers from 12-week-old littermate male mic...
<p>For each organ, the severity score is highest in the hu7/8 BAC+ x <i>MyD88</i> WT mice (left grou...
<p>Spongiosis, astrogliosis, and PrP deposition were ranked for severity and grouped by days post in...
<p>(A) Representative images of paraffin kidney sections stained with HE in control (CTL) and <i>Ppa...
<p>Hyperplasia was observed in some tissues (ovary and prostate: indicated by arrows). All mice were...
<p>Proliferation rates of pancreas, mammary gland, ovary, prostate (dorsolateral lobe), and bladder ...
Detailed histopathological diagnoses of inbred mouse strains are important for interpreting research...
The 129 mouse strain is commonly used for the generation of genetically engineered mice. Genetic dri...
The 129 mouse strain is commonly used for the generation of genetically engineered mice. Genetic dri...
<p>Histological findings in CXCL10 KO, and HBZ-Tg/CXCL10 KO mice at 24 weeks of age.</p
<p>(A) Photographs show dorsal aspect of <i>OX40<sup>Cre</sup> Ikbk2<sup>fx/fx</sup></i> mice with v...
<p>Histological findings in WT, HBZ-Tg, IFN-γ KO, and HBZ-Tg/IFN-γ KO mice at 24 weeks of age.</p
<p>(A) Representative images of Hematoxylin & Eosin (HE) stained livers from young (12-week-old) lit...
<p>Development of foci of cellular alteration (FCA), the proliferating cell nuclear antigen (PCNA)-l...
<p>(A) Photograph shows skin pathology in a representative <i>Rag1</i><sup>−/− </sup><i>OX40<sup>Cre...
<p>(A) Representative images of Masson trichrome stained livers from 12-week-old littermate male mic...
<p>For each organ, the severity score is highest in the hu7/8 BAC+ x <i>MyD88</i> WT mice (left grou...
<p>Spongiosis, astrogliosis, and PrP deposition were ranked for severity and grouped by days post in...
<p>(A) Representative images of paraffin kidney sections stained with HE in control (CTL) and <i>Ppa...