<p>Sequence of LBD of AR in 104-S, 104-R1, and 104-R2 cells based on forward primer (A) and reverse primer (B) was shown. Red arrow indicated the point mutation T877A on LBD of AR in LNCaP cells.</p
textabstractAmong nuclear receptors, the androgen receptor (AR) is unique in that its ligand-b...
<p>(<b>A</b>) Selective mutants of solvent-exposed residues that are highly conserved across differe...
(A) The intron-exon structure of the gene. The novel mutations are shown in bold. (B) Different doma...
<p>(A) Cytogenetic analysis of AR status in normal male control and E006AA cells as determined by Fl...
<p>LNCaP cells stably overexpressing AR constructs or vector control were derived by retrovirus-medi...
<p>Docking program WILMA was used to examine structural changes of the ligand-binding domain of the ...
The androgen receptor (AR) mediates the various actions of androgens and is responsible for the male...
DBD * is a novel gene encoding an 89 amino acid peptide that is constitutively lethal to leukemic ce...
DNA binding as well as ligand binding by nuclear receptors has been studied extensively. Both bindin...
<p>(A) LNCaP cells stably overexpressing vector or AR constructs were grown in phenol red free media...
DNA binding as well as ligand binding by nuclear receptors has been studied extensively. Both bindin...
Liver X receptors (LXRs) are nuclear receptors that regulate the metabolism of cholesterol and bile ...
<p>(A). Distribution of <i>NR5A1</i> mutations in relation to the functional domains of the protein....
<p>(A) Triple mutant D77T/L117Q/I196P: key agonist binding residues (yellow) and point mutations (re...
<p><b>A</b> The location of the de novo mutations in LRP6 are shown relative to the key protein doma...
textabstractAmong nuclear receptors, the androgen receptor (AR) is unique in that its ligand-b...
<p>(<b>A</b>) Selective mutants of solvent-exposed residues that are highly conserved across differe...
(A) The intron-exon structure of the gene. The novel mutations are shown in bold. (B) Different doma...
<p>(A) Cytogenetic analysis of AR status in normal male control and E006AA cells as determined by Fl...
<p>LNCaP cells stably overexpressing AR constructs or vector control were derived by retrovirus-medi...
<p>Docking program WILMA was used to examine structural changes of the ligand-binding domain of the ...
The androgen receptor (AR) mediates the various actions of androgens and is responsible for the male...
DBD * is a novel gene encoding an 89 amino acid peptide that is constitutively lethal to leukemic ce...
DNA binding as well as ligand binding by nuclear receptors has been studied extensively. Both bindin...
<p>(A) LNCaP cells stably overexpressing vector or AR constructs were grown in phenol red free media...
DNA binding as well as ligand binding by nuclear receptors has been studied extensively. Both bindin...
Liver X receptors (LXRs) are nuclear receptors that regulate the metabolism of cholesterol and bile ...
<p>(A). Distribution of <i>NR5A1</i> mutations in relation to the functional domains of the protein....
<p>(A) Triple mutant D77T/L117Q/I196P: key agonist binding residues (yellow) and point mutations (re...
<p><b>A</b> The location of the de novo mutations in LRP6 are shown relative to the key protein doma...
textabstractAmong nuclear receptors, the androgen receptor (AR) is unique in that its ligand-b...
<p>(<b>A</b>) Selective mutants of solvent-exposed residues that are highly conserved across differe...
(A) The intron-exon structure of the gene. The novel mutations are shown in bold. (B) Different doma...