Viral loads in chronic infection after Treg depletion and/or blocking of inhibitory pathways.

<p>(<b>A</b>) Spleens of chronically FV-infected mice from the different treatment groups were analyzed for viral loads by infectious center assays 1 day after termination of treatment. Each dot represents an individual mouse. Data were pooled from 4 to 6 independent experiments with similar results. Statistically significant differences are indicated by asterisks (*<0.05; ***<0.0005; analysis of variance [ANOVA] nonparametric, Dunn's multiple comparison test). (<b>B</b>) To study long-term effects of the treatment spleens of mice from the different groups were analyzed for viral loads by infectious center assay at 21 days post treatment (dpt). Each dot represents an individual mouse.