Enantioselective synthesis of functionalized cyclic allylic alcohols via dynamic kinetic resolution has been developed. Cyclopentadienylruthenium catalysts were used for the racemization, and lipase PS-IM or CALB was employed for the resolution. By optimization of the reaction conditions the formation of the enone byproduct was minimized, making it possible to prepare a range of optically active functionalized allylic alcohols in good yields and high ee’s
Dynamic kinetic resolution (DKR) is a powerful method for obtaining compounds with high optical puri...
We explored the kinetic resolution of 31 different diarylmethanols with an activated lipoprotein lip...
Horino S, Nishio T, Kawanishi S, et al. Enantiodivergent Chemoenzymatic Dynamic Kinetic Resolution: ...
A synthetic protocol making use of a well-defined cationic ruthenium complex 2 enabling the racemiza...
We report the dynamic kinetic resolution (DKR) of various secondary alcohols by the combination of a...
The combination of enzyme and metal catalysis is described as a useful method for the synthesis of o...
DoctorDynamic kinetic resolution (DKR) provides a practical method for the conversion of racemic sub...
The major part of this thesis describes the synthesis of enantiopure alcohols and diols by combining...
Enzyme-metal combo catalysis is described as a useful methodology for the synthesis of optically act...
The major part of this thesis describes the synthesis of enantiopure alcohols and diols by combining...
The scale-up of the ruthenium- and enzyme-catalyzed dynamic kinetic resolution (DKR) of (rac)-1-phen...
The enzymatic resolution of racemic substrates now is a well- established approach for the synthesis...
A nonenzymatic dynamic kinetic resolution of acyclic and cyclic benzylic alcohols is reported. The a...
In this paper, we have shown that the [RuCl2(p-cymene)] 2 complex associated with simple hemisalen l...
We have discovered that the racemization of configurationally stable, axially chiral 2,2′‐dihydroxy‐...
Dynamic kinetic resolution (DKR) is a powerful method for obtaining compounds with high optical puri...
We explored the kinetic resolution of 31 different diarylmethanols with an activated lipoprotein lip...
Horino S, Nishio T, Kawanishi S, et al. Enantiodivergent Chemoenzymatic Dynamic Kinetic Resolution: ...
A synthetic protocol making use of a well-defined cationic ruthenium complex 2 enabling the racemiza...
We report the dynamic kinetic resolution (DKR) of various secondary alcohols by the combination of a...
The combination of enzyme and metal catalysis is described as a useful method for the synthesis of o...
DoctorDynamic kinetic resolution (DKR) provides a practical method for the conversion of racemic sub...
The major part of this thesis describes the synthesis of enantiopure alcohols and diols by combining...
Enzyme-metal combo catalysis is described as a useful methodology for the synthesis of optically act...
The major part of this thesis describes the synthesis of enantiopure alcohols and diols by combining...
The scale-up of the ruthenium- and enzyme-catalyzed dynamic kinetic resolution (DKR) of (rac)-1-phen...
The enzymatic resolution of racemic substrates now is a well- established approach for the synthesis...
A nonenzymatic dynamic kinetic resolution of acyclic and cyclic benzylic alcohols is reported. The a...
In this paper, we have shown that the [RuCl2(p-cymene)] 2 complex associated with simple hemisalen l...
We have discovered that the racemization of configurationally stable, axially chiral 2,2′‐dihydroxy‐...
Dynamic kinetic resolution (DKR) is a powerful method for obtaining compounds with high optical puri...
We explored the kinetic resolution of 31 different diarylmethanols with an activated lipoprotein lip...
Horino S, Nishio T, Kawanishi S, et al. Enantiodivergent Chemoenzymatic Dynamic Kinetic Resolution: ...