Correlation of PTEN and PLZF expressions in prostate cancer tissues.

<p>A. The representative immunohistochemical staining for PTEN and PLZF of human prostate cancer specimens of low (GS = 5, 6), moderate (GS = 7) and high grades (GS = 8, 9) by the Gleason score. Scale bar, 50 µm. B, C. The mean staining scores of PTEN (B) and PLZF (C) were evaluated in low, moderate and high grades of prostate cancer specimens. Data were shown as mean ± SD. The <i>P</i> values for comparison between line-linked groups were gotten by Student's <i>t</i>-test. D. Box plot of PLZF staining score in tumors with low and high PTEN expression. Horizontal lines represent the median; the bottom and top of the boxes represent the 25th and 75th percentiles, respectively; and the vertical bars represent the range of data. Data were analyzed by Pearson's chi-square test. E. The percentage of tumors with high and low PLZF expression in the PTEN^high and PTEN^low groups of subjects. Data were analyzed by Spearman-rank correlation.