<div><p>ChIp analysis of Sirt1 enrichment at rDNA, HM loci, telomeric and sub telomeric regions in <i>sir2Δ</i>+ and <i>sir2Δ</i>- strains during <i>SIRT1</i> induction (galactose medium). Sirt1 enrichment for <i>sir2Δ</i>+ was referred to <i>sir2Δ</i>- levels =1. Histograms averages and Std. Dev. bars are representative of three technical replicates for at least three biological replicates performed. </p> <p>Statistical analysis as in Figure 3.</p></div
<p>HeLa cells were transfected with GFP, and wild-type or H187Y GFP-SIRT2 and 48 hours after transfe...
<p><b>A)</b> The genotype for rs7895833 SNP of <i>SIRT1</i> gene. <b>B)</b> The genotype for rs70691...
<p>(A) Mediator association at the indicated <i>GAL</i> regions in cells grown in galactose (gal) or...
<div><p>RT-PCR transcriptional analysis in WT and <i>sir2Δ</i> strains transformed with empty plasmi...
<div><p>(A) Western blot analysis of H3K9, H4K16, H4K12 global acetylation after <i>SIRT1</i> overni...
<div><p>A) Southern blot analysis of ERCs species in WT and <i>sir2Δ</i> with <i>SIRT1</i> construct...
(A) Illustration of 3000 bp from the left telomere of chromosome 3 in the Integrative Genome Viewer ...
<p><b>A)</b> Telomeric Silencing Assay comparing Δhmt1/Δrpd3 to either Δhmt1 or Δrpd3 single mutant....
<p>(<b>A</b>) Schematic representation of TRβ1 response regions (TREs) of TRβ1 target genes with seq...
<p>(A–D) qPCR analysis of HepG2-TRβ1 cells extracts treated +/− T<sub>3</sub> and SIRT1 siRNA. G-6-P...
<p>(<b>A</b>) Peak normalized and (<b>B</b>) telomere length adjusted ChIP data for Trt1<sup>TERT</s...
<p>(a) Association of Est2 with a telomere and a recombination substrate in wild type cells. Wild ty...
<p>(A) CIN612 cells stably transduced with shGFP control or two shSIRT1 constructs were induced to d...
Illustrations of a 3000 bp region of the indicated telomeres in the Integrative Genome Viewer (IGV)....
<p>(A) Northern analysis of siRNA isolated from the indicated strains using oligonucleotide probes s...
<p>HeLa cells were transfected with GFP, and wild-type or H187Y GFP-SIRT2 and 48 hours after transfe...
<p><b>A)</b> The genotype for rs7895833 SNP of <i>SIRT1</i> gene. <b>B)</b> The genotype for rs70691...
<p>(A) Mediator association at the indicated <i>GAL</i> regions in cells grown in galactose (gal) or...
<div><p>RT-PCR transcriptional analysis in WT and <i>sir2Δ</i> strains transformed with empty plasmi...
<div><p>(A) Western blot analysis of H3K9, H4K16, H4K12 global acetylation after <i>SIRT1</i> overni...
<div><p>A) Southern blot analysis of ERCs species in WT and <i>sir2Δ</i> with <i>SIRT1</i> construct...
(A) Illustration of 3000 bp from the left telomere of chromosome 3 in the Integrative Genome Viewer ...
<p><b>A)</b> Telomeric Silencing Assay comparing Δhmt1/Δrpd3 to either Δhmt1 or Δrpd3 single mutant....
<p>(<b>A</b>) Schematic representation of TRβ1 response regions (TREs) of TRβ1 target genes with seq...
<p>(A–D) qPCR analysis of HepG2-TRβ1 cells extracts treated +/− T<sub>3</sub> and SIRT1 siRNA. G-6-P...
<p>(<b>A</b>) Peak normalized and (<b>B</b>) telomere length adjusted ChIP data for Trt1<sup>TERT</s...
<p>(a) Association of Est2 with a telomere and a recombination substrate in wild type cells. Wild ty...
<p>(A) CIN612 cells stably transduced with shGFP control or two shSIRT1 constructs were induced to d...
Illustrations of a 3000 bp region of the indicated telomeres in the Integrative Genome Viewer (IGV)....
<p>(A) Northern analysis of siRNA isolated from the indicated strains using oligonucleotide probes s...
<p>HeLa cells were transfected with GFP, and wild-type or H187Y GFP-SIRT2 and 48 hours after transfe...
<p><b>A)</b> The genotype for rs7895833 SNP of <i>SIRT1</i> gene. <b>B)</b> The genotype for rs70691...
<p>(A) Mediator association at the indicated <i>GAL</i> regions in cells grown in galactose (gal) or...