Effect of MAPK inhibitors on cellular responses (in terms of Cell viability and LDH release) in MH-S cells infected with <i>M. immunogenum</i> 700506.

<p>A. Demonstration of the effect of the p38 inhibitor (SB202190) and JNK inhibitor (SP600125), each at 20 µM concentrations, in comparison with the no-inhibitor control (positive control) and vehicle control (negative control). Asterisk (*) and pound sign (#) indicate statistically significant (P≤0.05) difference from the vehicle control and 700506 (no inhibitor) control, respectively. B. Dose-dependent effect of p38 inhibitor (SB202190) and JNK inhibitor (SP600125) on the cellular responses using 20 µM and 40 µM concentrations. Asterisks (**) indicate statistically significant (P≤0.001) difference between different concentrations of inhibitor. Values are presented as means ± standard deviations calculated based on the data obtained from three independent experiments; each experiment was done in triplicate.