Comparison between the physicochemical properties of the wildtype and the mutant models for each of the data sets.

<p>Plots showing the differences between (A) Modeller DOPE scores for the wild type and mutant model (based on 3D, 10,628 mutations, and Humsavar sets, 21,446 residues), (B) changes in hydrophobicity between wild type and mutant in both sets and (C) changes in size between wild type and mutation in both sets.