<p>Frozen kidney sections were cut and dissolved in TRIzol to isolate RNA. Renal mRNA levels of TLR2 (A) and TLR4 (B) were determined in WT (black bars), TREM1/3 KO (white bars) and DAP12 KO (grey bars) 1, 3, 7 and 14 days following UUO. Contralateral unobstructed kidney 1 day after UUO was used as control (C1). Gene expression is relatively expressed to housekeeping gene TBP and control is adjusted to relative expression of 1. *P<0.05, **P<0.01 versus WT at indicated time point.</p
Ischemia and reperfusion injury (IR) is an antigen independent inflammatory process that causes tiss...
<p><b>(A–C)</b><i>Tlr2–4<sup>−/−</sup></i><b>(D–F)</b><i>Myd88<sup>−/−</sup></i> mice or respective ...
Ischemia and reperfusion injury (IR) is an antigen independent inflammatory process that causes tiss...
<p>Frozen kidney sections were cut and dissolved in TRIzol to isolate RNA. Renal mRNA levels of Sigl...
<p>Frozen kidney sections were cut and dissolved in TRIzol (A+B) or RIPA buffer (C) to isolate RNA a...
<p>Wildtype mice underwent surgery and UUO kidneys (black bars) or contralateral kidneys (Co, grey b...
<p>The amount of TLR2 mRNA (A) and protein (B) was markedly upregulated after UUO injury. Data are m...
<p>Data are mean ± SD; number of animals within the bars. (A and B) Serum urea and creatinine levels...
<p>Renal function and injury of wild type mice reconstituted with TLR4−/− bone marrow (WT+KO BM, whi...
<p>Measurements were carried out in heart tissues at the times after I/R given on the abscissae. In ...
<p>(A), Representative images of immunohistochemical staining of kidney sections from mice in the sa...
&<p>Data are given as fold change (± SD) compared with gene expression in pre-nephritic mice.</p
<p>mRNA expression of TLR4 and its ligands in kidney was upregulated at 10 weeks after diabetes indu...
<p>A. Wildtype mice underwent surgery and UUO kidneys (black bars) or contralateral kidneys (Co, gre...
<p><b>(A–B)</b><b> </b> Q-PCR showing <i>Il-1β</i> and <i>Trem1</i> expression in BMDMφ stimulated f...
Ischemia and reperfusion injury (IR) is an antigen independent inflammatory process that causes tiss...
<p><b>(A–C)</b><i>Tlr2–4<sup>−/−</sup></i><b>(D–F)</b><i>Myd88<sup>−/−</sup></i> mice or respective ...
Ischemia and reperfusion injury (IR) is an antigen independent inflammatory process that causes tiss...
<p>Frozen kidney sections were cut and dissolved in TRIzol to isolate RNA. Renal mRNA levels of Sigl...
<p>Frozen kidney sections were cut and dissolved in TRIzol (A+B) or RIPA buffer (C) to isolate RNA a...
<p>Wildtype mice underwent surgery and UUO kidneys (black bars) or contralateral kidneys (Co, grey b...
<p>The amount of TLR2 mRNA (A) and protein (B) was markedly upregulated after UUO injury. Data are m...
<p>Data are mean ± SD; number of animals within the bars. (A and B) Serum urea and creatinine levels...
<p>Renal function and injury of wild type mice reconstituted with TLR4−/− bone marrow (WT+KO BM, whi...
<p>Measurements were carried out in heart tissues at the times after I/R given on the abscissae. In ...
<p>(A), Representative images of immunohistochemical staining of kidney sections from mice in the sa...
&<p>Data are given as fold change (± SD) compared with gene expression in pre-nephritic mice.</p
<p>mRNA expression of TLR4 and its ligands in kidney was upregulated at 10 weeks after diabetes indu...
<p>A. Wildtype mice underwent surgery and UUO kidneys (black bars) or contralateral kidneys (Co, gre...
<p><b>(A–B)</b><b> </b> Q-PCR showing <i>Il-1β</i> and <i>Trem1</i> expression in BMDMφ stimulated f...
Ischemia and reperfusion injury (IR) is an antigen independent inflammatory process that causes tiss...
<p><b>(A–C)</b><i>Tlr2–4<sup>−/−</sup></i><b>(D–F)</b><i>Myd88<sup>−/−</sup></i> mice or respective ...
Ischemia and reperfusion injury (IR) is an antigen independent inflammatory process that causes tiss...