rsfMRI analysis.

<p>After the pre-processing steps, all rsfMRI data were analysed using the REST-toolbox. 1) Whole brain seed correlation analysis: The smoothed data and masks for every seed region were loaded and the filter was set between 0.01 and 0.1 Hz. Time courses of the low frequency fluctuations of the BOLD-signal were computed for each seed region from each subject. The functional correlation between the time courses of each seed region was calculated and the correlation coefficients were z-transformed, resulting in functional connectivity (FC) matrices for each subject. Then, the mean z-transformed FC matrices were calculated for the WT and TG groups. 2) Pairwise seed correlation analyses: Interhemispheric FC (hatched regions) was assessed between each seed region in the left hemisphere (yellow) and the corresponding region in the right hemisphere. Then, mean z-transformed FC maps of the WT and TG groups were computed in SPM.