Differential expression of antiviral factors in the placental tissues of HIV-infected mothers and CB samples.

<p>A) Decidua (n=10-13) and placental chorionic villi (n=9-13) from HIV-infected mothers (closed symbols) and UN mothers (open symbols) were assessed for A3G, A3F, TRIM-5α, α1-defensin, IFN-β, tetherin and STING expression using real-time PCR. The data represent median values. B) Immunoblot analysis of A3G, A3F and TRIM5α protein in decidua (n=5-6) and villi (n=4-6) from infected mothers (+, closed symbols) and UN mothers (-, open symbols). The data represent median values.*p≤0.05 compared with the control group; ++p≤0.01 compared with the mother group.