The rs640249A-rs641563A haplotype is associated with resistance to CCC.
- Amanda Farage Frade (499727)
- Priscila Camilo Teixeira (499728)
- Barbara Maria Ianni (124949)
- Cristina Wide Pissetti (354862)
- Bruno Saba (124980)
- Lin Hui Tzu Wang (499729)
- Andréia Kuramoto (499730)
- Luciana Gabriel Nogueira (124941)
- Paula Buck (125000)
- Fabrício Dias (124975)
- Helene Giniaux (499731)
- Agnes Llored (499732)
- Sthefanny Alves (499733)
- Andre Schmidt (3262995)
- Eduardo Donadi (124970)
- José Antonio Marin-Neto (499734)
- Mario Hirata (499735)
- Marcelo Sampaio (124992)
- Abílio Fragata (5657260)
- Edimar Alcides Bocchi (125008)
- Antonio Noedir Stolf (499736)
- Alfredo Inacio Fiorelli (5657263)
- Ronaldo Honorato Barros Santos (124945)
- Virmondes Rodrigues (499737)
- Alexandre Costa Pereira (319788)
- Jorge Kalil (52916)
- Edecio Cunha-Neto (125019)
- Christophe Chevillard (499738)
Publication date
December 2013
DOIAbstract
<p>Based on the genotypes obtained, we performed a haplotype analysis of the rs7719175 and rs1800925 polymorphisms. Only three haplotypes were found in our study population: <b>A</b>) Distribution of the three main haplotype combinations in the CCC patients and ASY subjects: homozygous rs640249C-rs641563C (black bar); heterozygous rs640249C-rs641563C + rs640249A-rs641563A (gray bar) and homozygous rs640249A-rs641563A (white bar). <b>B</b>) Haplotype combinations between cases and controls, taking sex into account. <b>C</b>) Distribution of the three main haplotype combinations between patients with severe and moderate CCC, taking sex into account.</p
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