<p>Confocal microscopy of cerebellar sections of 10-month-old mice. (A,B,C,D) Maximum intensity projections of all channels analyzed. (A–B′″) Autofluorescent deposits (green) in Purkinje cells barely co-localized with EEA1 (red). (C–D′″) Autofluorescent deposits in knockout tissues were Lamp1-positive (clone CD107a). Scale bars: 10 µm.</p
<p><b>(A)</b> Photomicrographs illustrating double immunofluorescence experiments in the EC against ...
<p>(A) Scanning laser ophthalmoscope image of the retinae: Large clusters of hyperfluorescent foci (...
<p><b>(A, A´)</b> Overall Lamp1 levels are not changed in Spatacsin KO brains (Mean±SEM of n = 3 exp...
<p>(A,E) In knockout mice autofluorescent material (excited at 488 nm) was already observed in neuro...
<p><b>(A-D)</b> At 16 months of age we observed an accumulation of autofluoerscent material in corti...
<p>IHC staining of the cerebellum for Iba1 (A-C) and LAMP-1 (D-F). (A) Molecular layer of cerebellum...
<p>Confocal fluorescent microscopy of Prism JD1849 mice cerebellums at five different stages of deve...
<p>A) Confocal fluorescent microscopy in cerebellum from a P24 mouse shows distinct expression of Sn...
<p>(A). Spinal cords from C57BL/6 mice were stained with ASMA (red) and were further imaged by OPT. ...
<p>Sagittal sections through the medial cerebellum of adult wild type (A, D), <i>Apoer2</i> (B, E) o...
<p>All histological investigations show FTgpi177 <i>Prnp</i><sup>o/o</sup> mice; age-matched <i>Prnp...
<div><p>Aldolase C (Aldoc, also known as “zebrin II”), a brain type isozyme of a glycolysis enzyme, ...
A paradigm shift is occurring in neuroscience and in general in life sciences converting biomedical ...
<p>40(red) were injected into the lumen of the SI and 30 minutes later the SI was excised, Peyer's p...
<p>Mice were i.v. injected with GFP-Etx-I51C/A114C (A–B) or GFP-Etx-V56C/A118C (C–D) in combination ...
<p><b>(A)</b> Photomicrographs illustrating double immunofluorescence experiments in the EC against ...
<p>(A) Scanning laser ophthalmoscope image of the retinae: Large clusters of hyperfluorescent foci (...
<p><b>(A, A´)</b> Overall Lamp1 levels are not changed in Spatacsin KO brains (Mean±SEM of n = 3 exp...
<p>(A,E) In knockout mice autofluorescent material (excited at 488 nm) was already observed in neuro...
<p><b>(A-D)</b> At 16 months of age we observed an accumulation of autofluoerscent material in corti...
<p>IHC staining of the cerebellum for Iba1 (A-C) and LAMP-1 (D-F). (A) Molecular layer of cerebellum...
<p>Confocal fluorescent microscopy of Prism JD1849 mice cerebellums at five different stages of deve...
<p>A) Confocal fluorescent microscopy in cerebellum from a P24 mouse shows distinct expression of Sn...
<p>(A). Spinal cords from C57BL/6 mice were stained with ASMA (red) and were further imaged by OPT. ...
<p>Sagittal sections through the medial cerebellum of adult wild type (A, D), <i>Apoer2</i> (B, E) o...
<p>All histological investigations show FTgpi177 <i>Prnp</i><sup>o/o</sup> mice; age-matched <i>Prnp...
<div><p>Aldolase C (Aldoc, also known as “zebrin II”), a brain type isozyme of a glycolysis enzyme, ...
A paradigm shift is occurring in neuroscience and in general in life sciences converting biomedical ...
<p>40(red) were injected into the lumen of the SI and 30 minutes later the SI was excised, Peyer's p...
<p>Mice were i.v. injected with GFP-Etx-I51C/A114C (A–B) or GFP-Etx-V56C/A118C (C–D) in combination ...
<p><b>(A)</b> Photomicrographs illustrating double immunofluorescence experiments in the EC against ...
<p>(A) Scanning laser ophthalmoscope image of the retinae: Large clusters of hyperfluorescent foci (...
<p><b>(A, A´)</b> Overall Lamp1 levels are not changed in Spatacsin KO brains (Mean±SEM of n = 3 exp...