Comparison between RNA-seq and exome-seq.

<p>Variant Allele Frequency plots for evaluating two RNA-seq mapping strategies for two example samples, namely the RPMI8402 cell line (<b>A</b>, <b>B</b>) and the TLE79 patient sample (<b>C</b>, <b>D</b>). On the left are the results of mapping with TopHat 1.3.3. (<b>A</b>,<b>C</b>), while on the right are the results of mapping with TopHat 2.0.5 with forced re-mapping of all reads to the genome. The SNVs that have at least 20 reads in exome-seq and RNA-seq are plotted. Red and green dots represent the SNVs that are detected only in RNA-seq and only in exome-seq, respectively, while black dots represent the SNVs that are called in both. Venn diagrams are produced from the points represented in the graphs.