Point mutations and gene fusions organized into functional categories.

<p>Protein altering mutations and INDELs, alternative splicing events and validated fusions are shown. Red boxes indicate protein-altering mutations (i.e. nonsense, missense and splice site mutations); purple boxes indicate frame-shift INDELs whereas blue, green and orange boxes represent fusion events resulting in over-expression of the partner gene, inactivation of the partner gene or generation of a chimeric protein, respectively, and finally black boxes indicating alternative splicing events.