Effects of Bb-elicited IL-10 on the production of proinflammatory cytokines by MØs and DCs <i>in</i><i>vitro</i>.

<p>MØs (upper panel) or DCs (lower panel) derived from either wild type (wt) C57BL/6 or IL-10^-/- mice were co-cultured with Bb (MOI=10) at 37C^o. Culture supernatants were collected at the indicated times post-stimulation and cytokine content assessed by ELISA. Each symbol represents the average of triplicate samples from at least three separate experiments. Statistically significant (P<0.05) values are indicated between Bb-stimulated versus unstimulated APCs (*), or stimulated B6 versus IL-10^-/- APCs (**).