Effects of Ad-NDRG2 intratumoral injections on tumor growth and long-term survival of 786-O cells tumor-bearing mice.

<p>(A) Tumor growth curve. The tumor growth was assessed every 3 days until Day 21 of treatment by measuring two perpendicular diameters and calculating the volume in mm³. Statistical analysis was assessed with one-way ANOVA. ** or *** indicates P < 0.01 or P < 0.001 when compared with the Ad-LacZ group. (B) Kaplan–Meier curve was shown in the Control, Ad-LacZ and Ad-NDRG2 groups, with each group consisting of ten mice. There was a significant difference between Ad-NDRG2 and Ad-LacZ treatments. Statistical significance was assessed using log-rank tests. ** indicates <i>P</i> < 0.01 when compared with the Ad-LacZ group.