Autophagy gene expression in hypothalamic tissue of BACHD mice.

<p>Selected autophagy markers analyzed by qRT-PCR in hypothalamic tissue from BACHD mice at 2, 6 and 12 months of age and compared with gender- and age-matched controls (n = 3–6/group). The data in the table are expressed as mean fold change ± SEM, relative to 2 months wt. Statistical significance was considered when p<0.05 and analysis were performed using two-factor ANOVA followed by post-hoc test or one-factor ANOVA followed by post-hoc test (*represents genotype effect while # represents age effect). For more detailed information see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0083050#pone.0083050.s007" target="_blank">Statistical Results S1</a>.