<p>Selected autophagy markers were analyzed by Western blot of striatal tissue from BACHD mice at 2, 6 and 12 months of age and compared with gender- and age-matched controls (n = 3–6/group). The data show that the basal levels of autophagy were unaltered in the striatum of BACHD mice. The data in the graphs are expressed as mean ± SEM, relative to the 2 months wt controls. The Western blots are representative of one sample for each group.</p
<p>Immunoblot analysis of LC3A and LC3B in tissue extractions of skeletal muscles of WT (n = 6) and ...
<p>Microarray analysis of autophagy-related gene expression in the striatum and hypothalamus of mice...
<p>Immunohistochemical histological analyses comparing WT and heterozygote VCP<sup><b>R155H/+</b></s...
<p>The expression levels of selected autophagy markers were analyzed by Western blot in cortical tis...
<p>Selected autophagy markers analyzed by qRT-PCR in tissue from striata from BACHD mice at 2, 6 and...
<p>Selected autophagy markers analyzed by qRT-PCR in tissue from cerebral cortex from BACHD mice at ...
<p>Selected autophagy markers analyzed by qRT-PCR in hypothalamic tissue from BACHD mice at 2, 6 and...
<p>The expression levels of selected autophagy markers were analyzed by Western blot in mice bilater...
<p>Relative expression values of <i>Lc3</i>, <i>p62</i>, <i>Beclin1</i>, <i>Atg5</i> and <i>E2f1</i>...
Although macroautophagy (MA) has been shown to decline with age, whether these changes are manifest ...
<p>A) Accumulation of autophagosomes was assessed by determining the levels of the autophagic marker...
<p>(A) Nissl-stained sections of wt and 14-3-3ζtg mice. Scale bar, (top) 600 µm; (bottom), 330 µm. (...
<p>(A), Representative images of Immunostaining of LC3 on paraffin section of hearts from high over-...
Huntington's disease (HD) is a fatal neurodegenerative disorder caused by an expanded polyglutamine ...
Abstract Impaired or deficient autophagy is believed to cause or contribute to aging, as well as sev...
<p>Immunoblot analysis of LC3A and LC3B in tissue extractions of skeletal muscles of WT (n = 6) and ...
<p>Microarray analysis of autophagy-related gene expression in the striatum and hypothalamus of mice...
<p>Immunohistochemical histological analyses comparing WT and heterozygote VCP<sup><b>R155H/+</b></s...
<p>The expression levels of selected autophagy markers were analyzed by Western blot in cortical tis...
<p>Selected autophagy markers analyzed by qRT-PCR in tissue from striata from BACHD mice at 2, 6 and...
<p>Selected autophagy markers analyzed by qRT-PCR in tissue from cerebral cortex from BACHD mice at ...
<p>Selected autophagy markers analyzed by qRT-PCR in hypothalamic tissue from BACHD mice at 2, 6 and...
<p>The expression levels of selected autophagy markers were analyzed by Western blot in mice bilater...
<p>Relative expression values of <i>Lc3</i>, <i>p62</i>, <i>Beclin1</i>, <i>Atg5</i> and <i>E2f1</i>...
Although macroautophagy (MA) has been shown to decline with age, whether these changes are manifest ...
<p>A) Accumulation of autophagosomes was assessed by determining the levels of the autophagic marker...
<p>(A) Nissl-stained sections of wt and 14-3-3ζtg mice. Scale bar, (top) 600 µm; (bottom), 330 µm. (...
<p>(A), Representative images of Immunostaining of LC3 on paraffin section of hearts from high over-...
Huntington's disease (HD) is a fatal neurodegenerative disorder caused by an expanded polyglutamine ...
Abstract Impaired or deficient autophagy is believed to cause or contribute to aging, as well as sev...
<p>Immunoblot analysis of LC3A and LC3B in tissue extractions of skeletal muscles of WT (n = 6) and ...
<p>Microarray analysis of autophagy-related gene expression in the striatum and hypothalamus of mice...
<p>Immunohistochemical histological analyses comparing WT and heterozygote VCP<sup><b>R155H/+</b></s...