<p>The number of residue variations that have an evolutionary origin (i.e., a similar variation that is observed in at least one homologous sequence) and those that are novel are indicated for cancer mutations in EGFR, ALK and Abl1.</p
Diseases with readily available therapies may eventually prevail against the specific treatment by t...
The emergence of mutations that confer resistance to molecularly targeted therapeutics is dependent ...
<p>Mutation frequency of amino acid residues involved in hydrophobic interaction with FMN.</p
Several tumour types are sensitive to deactivation of just one or very few genes that are constantly...
Several tumour types are sensitive to deactivation of just one or very few genes that are constantly...
Cancer can be viewed as a set of different diseases with distinctions based on tissue origin, driver...
Cancer can be viewed as a set of different diseases with distinctions based on tissue origin, driver...
The process of natural selection acts both on individual organisms within a population and on indivi...
<div><p>The 1000 Genomes Project data provides a natural background dataset for amino acid germline ...
The 1000 Genomes Project data provides a natural background dataset for amino acid germline mutation...
Boning up on mutations: assessing the significance of candidate disease-causing DNA sequence variati...
Snapshots from the MutaGene server show the results of analysis of EGFR gene with a Pan-cancer model...
We have investigated the properties of three sets of human missense genetic variations: cancer somat...
<p>The structures of EGFR <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0082...
Prevalence of mutations identified in clusters by phylogenetic analysis of 251 sequences with drug r...
Diseases with readily available therapies may eventually prevail against the specific treatment by t...
The emergence of mutations that confer resistance to molecularly targeted therapeutics is dependent ...
<p>Mutation frequency of amino acid residues involved in hydrophobic interaction with FMN.</p
Several tumour types are sensitive to deactivation of just one or very few genes that are constantly...
Several tumour types are sensitive to deactivation of just one or very few genes that are constantly...
Cancer can be viewed as a set of different diseases with distinctions based on tissue origin, driver...
Cancer can be viewed as a set of different diseases with distinctions based on tissue origin, driver...
The process of natural selection acts both on individual organisms within a population and on indivi...
<div><p>The 1000 Genomes Project data provides a natural background dataset for amino acid germline ...
The 1000 Genomes Project data provides a natural background dataset for amino acid germline mutation...
Boning up on mutations: assessing the significance of candidate disease-causing DNA sequence variati...
Snapshots from the MutaGene server show the results of analysis of EGFR gene with a Pan-cancer model...
We have investigated the properties of three sets of human missense genetic variations: cancer somat...
<p>The structures of EGFR <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0082...
Prevalence of mutations identified in clusters by phylogenetic analysis of 251 sequences with drug r...
Diseases with readily available therapies may eventually prevail against the specific treatment by t...
The emergence of mutations that confer resistance to molecularly targeted therapeutics is dependent ...
<p>Mutation frequency of amino acid residues involved in hydrophobic interaction with FMN.</p
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